Singapore Eye Research Institute, Singapore National Eye Centre.
Duke-NUS Medical School.
J Glaucoma. 2020 Jan;29(1):60-66. doi: 10.1097/IJG.0000000000001355.
Primary angle closure disease (PACD) covers a spectrum that includes primary angle closure suspect, primary angle closure, primary angle closure glaucoma, and acute primary angle closure. Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomic or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography technology have further enhanced our understanding of the risk factors and mechanisms involved in the disease process. This review discusses the potential clinical role of the anterior segment optical coherence tomography in the diagnosis, mechanistic evaluation, and as a predictor for future clinical outcomes of patients with PACD.
原发性闭角型青光眼（PACG）包括一系列疾病，如原发性闭角型青光眼可疑、原发性闭角型青光眼、原发性闭角型青光眼和急性原发性闭角型青光眼。越来越多的证据表明，PACG 的发病机制复杂，多种致病因素包括前房角结构的解剖或生物测量特征的变化。眼前节光学相干断层扫描技术的进步进一步增强了我们对疾病过程中涉及的危险因素和机制的理解。本综述讨论了眼前节光学相干断层扫描在 PACG 患者的诊断、机制评估以及预测未来临床结局方面的潜在临床作用。
