Graduate Program on Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Musculoskelet Sci Pract. 2019 Dec;44:102054. doi: 10.1016/j.msksp.2019.102054. Epub 2019 Aug 30.
The aim of this study was to empirically derive subgroups according to pain-related fear of movement beliefs using cluster analysis within a sample of TMD patients and asymptomatic volunteers.
129 volunteers participated in this cross-sectional study (34.78, standard deviation [SD]: 12.49 years; 92 TMD patients and 37 symptom-free volunteers). Mechanical pain sensitivity through pressure pain threshold (PPT) on orofacial and remote sites, kinesiophobia, pain catastrophizing, anxiety and depression were assessed. A cluster analysis was used to derive subgroups according to kinesiophobia scores (TSK/TMD).
Three subgroups were derived: cluster 1 (high kinesiophobia [n = 53], TSK score: 33, SD[standard deviation] = 2.9), cluster 2 (moderate kinesiophobia [n = 50], TSK score: 26.2, SD = 2.14) and cluster 3 (no/low kinesiophobia [n = 26], TSK score 12.12, SD = 2.08) which included patients with higher overall PPT and lower scores on psychosocial variables. The group with high kinesiophobia showed high levels of pain catastrophizing, anxiety, and orofacial pain-related disability compared to the other subgroups and mechanical pain hyperalgesia in remote site compared to the low-kinesiophobia group. Also, we found a greater prevalence of triple diagnosis for the high-kinesiophobia subgroup compared to the moderate kinesiophobia group - odds ratio: 12.6 (95% confidence interval [CI]: 3.31-43.52, p < 0.01).
These results suggested that patients with TMD and higher levels of kinesiophobia beliefs may show a more complex clinical feature, with high psychosocial distress, widespread mechanical pain sensitivity, and a more complex TMD disorder. In this way, we suggest a relationship between the number of TMD diagnoses and kinesiophobia severity.
本研究旨在通过对 TMD 患者和无症状志愿者样本进行聚类分析,根据与运动相关的疼痛恐惧信念得出亚组。
共有 129 名志愿者参与了这项横断面研究(年龄 34.78 岁,标准差[SD]为 12.49 岁;其中 92 名 TMD 患者和 37 名无症状志愿者)。通过对口腔和面颌部及远处部位的压痛阈(PPT)进行机械性疼痛敏度评估、运动恐惧回避、疼痛灾难化、焦虑和抑郁。采用聚类分析方法根据 TSK/TMD 评分得出运动恐惧回避的亚组。
得出 3 个亚组:组 1(高运动恐惧回避[53 例],TSK 评分:33,SD=2.9)、组 2(中运动恐惧回避[50 例],TSK 评分:26.2,SD=2.14)和组 3(无/低运动恐惧回避[26 例],TSK 评分:12.12,SD=2.08),包括总体 PPT 较高和心理社会变量得分较低的患者。与其他亚组相比,高运动恐惧回避组的疼痛灾难化、焦虑和口颌面疼痛相关残疾程度更高,与低运动恐惧回避组相比,远处部位的机械性疼痛敏化程度更高。此外,与中运动恐惧回避组相比,高运动恐惧回避组的三联诊断患病率更高 - 比值比:12.6(95%置信区间[CI]:3.31-43.52,p<0.01)。
这些结果表明,TMD 患者运动恐惧回避程度较高,可能表现出更复杂的临床特征,具有较高的心理社会困扰、广泛的机械性疼痛敏化和更复杂的 TMD 障碍。因此,我们建议 TMD 诊断数量与运动恐惧回避严重程度之间存在关系。