Institute for Solid State Physics, University of Tokyo, Kashiwa, Chiba 277-8581, Japan.
J Chem Phys. 2019 Sep 7;151(9):094903. doi: 10.1063/1.5113646.
The disk-to-vesicle transition of a fluid membrane with no spontaneous curvature is well described by the competition between edge line and curvature energies. However, the transition of asymmetric membranes with spontaneous curvatures is not yet understood. In this study, the shape of the fluid membrane patch with a constant spontaneous curvature and its closing transition to a vesicle is investigated using theory and meshless membrane simulations. It is confirmed that the (meta)stable and transient membranes are well approximated by spherical caps. The membrane Gaussian modulus can be estimated from the cup shape of membrane patches as well as from the transition probability, although the latter estimate gives slightly smaller negative values. Furthermore, the self-assembly dynamics of membranes are presented, in which smaller vesicles are formed at higher spontaneous curvatures, higher edge line tension, and lower density.
无自发曲率的流体膜从盘面到囊泡的转变很好地由边缘线和曲率能之间的竞争来描述。然而，具有自发曲率的不对称膜的转变尚未被理解。在这项研究中，通过理论和无网格膜模拟，研究了具有恒定自发曲率的流体膜片的形状及其向囊泡的闭合转变。证实了（亚）稳定和瞬态膜可以很好地用球形帽来近似。虽然后者的估计值给出了稍小的负值，但可以从膜片的杯形以及从转变概率来估计膜的高斯模量。此外，还呈现了膜的自组装动力学，其中在较高的自发曲率、较高的边缘线张力和较低的密度下形成较小的囊泡。
