Urology Institute, University Hospitals, Cleveland Medical Center, Cleveland, OH, USA.
Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Int Urol Nephrol. 2019 Dec;51(12):2137-2141. doi: 10.1007/s11255-019-02276-1. Epub 2019 Sep 6.
To evaluate the impact of a modified transurethral resection of prostate (mTURP) in patients with a history of pelvic fracture urethral injury (PFUI) status post-urethroplasty, and subsequent lower urinary tract symptoms (LUTS) refractory to medical therapy caused by benign prostatic hyperplasia (BPH).
Five patients were identified with a history of PFUI and a successful reconstruction of the urethra, who developed severe LUTS. After maximal medical therapy failed, these patients underwent a mTURP. Their continence status and voiding parameters were recorded before and after surgery.
Significant improvements in both post-void residual (172 ± 137.36 mL vs. 26.6 ± 24.44 mL), p = 0.026, and International Prostatic Symptom Score (23.6 ± 4.82 vs. 7.6 ± 4.30), p = 0.002 were observed in the study. Although maximum flow rate was not statistically significant, there was an overall improvement in Q in all patients (8.92 ± 3.71 vs. 16.78 ± 6.44 mL/sec). Furthermore, all patients remained continent after this modified intervention.
Our modified TURP provides an adjunctive option in the management of severe LUTS secondary to BPH in patients with a history of PFUI urethroplasty who are refractory to medical management. In our experience, the patients experienced a lasting response with no incontinence.
评估改良经尿道前列腺切除术(mTURP)在既往骨盆骨折尿道损伤(PFUI)尿道成形术后且随后因良性前列腺增生(BPH)导致的下尿路症状(LUTS)对药物治疗无效的患者中的影响。
确定了 5 例既往有 PFUI 和成功重建尿道病史且出现严重 LUTS 的患者。在最大药物治疗失败后,这些患者接受了 mTURP。记录了他们手术前后的控尿状态和排尿参数。
研究发现,患者的残余尿量(172 ± 137.36 mL 比 26.6 ± 24.44 mL,p = 0.026)和国际前列腺症状评分(23.6 ± 4.82 比 7.6 ± 4.30,p = 0.002)均有显著改善。尽管最大尿流率没有统计学意义,但所有患者的 Q 均有整体改善(8.92 ± 3.71 比 16.78 ± 6.44 mL/sec)。此外,所有患者在接受这种改良干预后仍保持控尿。
对于既往有 PFUI 尿道成形术病史且对药物治疗无效的因 BPH 导致的严重 LUTS 患者,我们的改良 TURP 为其提供了一种辅助治疗选择。根据我们的经验,患者的反应持久,无尿失禁。