Zilov V G, Khadartsev A A, Eskov V M, Ilyashenko L K
Tula State University, Tula, Russia.
Medical Institute, Tver, Russia.
Bull Exp Biol Med. 2019 Aug;167(4):419-423. doi: 10.1007/s10517-019-04540-x. Epub 2019 Sep 6.
A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to himself in 15 repetitions of tremorogram recording (in unchanged homeostasis). This poses serious problems for physiology and medicine, and in the context of transition to individualized medicine, this raises the question of how different people can be compared if they are statistically more similar than one person to himself.
一种新现象（或悖论），即例如在一组不同受试者中，样本（如震颤图）的统计稳定性高于处于稳态未变的同一受试者。与此同时，结果表明，在15次震颤图记录（稳态未变）中，15个不同受试者彼此之间（从统计学角度）比同一个人自身的15次记录更为相似。这给生理学和医学带来了严重问题，并且在向个性化医学转变的背景下，这引发了一个问题：如果不同的人在统计学上比同一个人自身更为相似，那么该如何对他们进行比较。
