Division of Aging and Geriatric Dentistry, Department of Oral Function and Morphology, Tohoku University Graduate School of Dentistry, Sendai, Japan; Japanese Red Cross Ishinomaki Hospital, Ishinomaki, Japan.
Division of Aging and Geriatric Dentistry, Department of Oral Function and Morphology, Tohoku University Graduate School of Dentistry, Sendai, Japan.
J Prosthodont Res. 2020 Jul;64(3):289-295. doi: 10.1016/j.jpor.2019.08.005. Epub 2019 Sep 5.
This study aimed to investigate the relationship between the bilateral maximum occlusal force (MOF) of full dental arches and all-cause mortality in a group of community-dwelling older males and females in Japan.
This 13-year prospective cohort study was conducted among 815 older adults (395 male and 420 female) aged 70 years or over (mean age ± standard deviation: 75.1 ± 4.5 years). Bilateral MOF in the intercuspal position was recorded with horseshoe-shaped pressure-sensitive film. Participants were grouped by gender into tertiles according to MOF. Demographic variables, chronicity, comorbidity, physical status, cognitive and psychological status, social functioning, and blood chemistry data were also assessed. Information regarding all-cause mortality and migration was obtained from the Sendai Municipal Authority. Cox proportional hazard modeling was performed to assess all-cause mortality during the follow-up period.
In total, 159 male and 109 female participants died over a median 12.9-year follow-up period, and the cumulative mortality significantly increased with lower MOF in both males and females. The multivariate Cox proportional hazard model demonstrated a significant increase in the risk of all-cause mortality associated with lower tertiles of MOF, relative to the upper tertile in males (hazard ratio: 1.62; 95% confidence interval: 1.05-2.51) and females (hazard ratio: 1.94; 95% confidence interval: 1.10-3.56).
There was a significant and independent association of bilateral MOF with all-cause mortality in community-dwelling elderly males and females in Japan. These findings suggested that maintenance of oral functioning contributes to general health.
本研究旨在探讨日本社区居住的老年男女全牙弓最大咬合力（MOF）与全因死亡率之间的关系。
这是一项为期 13 年的前瞻性队列研究，共纳入 815 名 70 岁及以上的老年人（男性 395 名，女性 420 名）（平均年龄±标准差：75.1±4.5 岁）。使用马蹄形压敏胶片记录正中位双侧 MOF。根据 MOF 将参与者按性别分为三分位组。还评估了人口统计学变量、慢性病、合并症、身体状况、认知和心理状况、社会功能以及血液化学数据。通过仙台市当局获得了关于全因死亡率和迁移的信息。使用 Cox 比例风险模型评估随访期间的全因死亡率。
共有 159 名男性和 109 名女性参与者在中位 12.9 年的随访期间死亡，并且在男性和女性中，MOF 越低，累积死亡率越高。多变量 Cox 比例风险模型显示，与男性（危险比：1.62；95%置信区间：1.05-2.51）和女性（危险比：1.94；95%置信区间：1.10-3.56）的上三分位相比，MOF 较低的 tertiles 与全因死亡率的风险显著增加。
在日本社区居住的老年男女中，双侧 MOF 与全因死亡率存在显著的独立相关性。这些发现表明，维持口腔功能有助于整体健康。
