Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden
BMJ Open. 2019 Sep 6;9(9):e031023. doi: 10.1136/bmjopen-2019-031023.
Currently, there are very few published studies on preinjury and postinjury assessments of quality of life (QoL) based on a prospective appraisal; specifically, knowledge of those who do not seek medical care following injury is lacking. To close these knowledge gaps, this study aims to identify the psychosocial consequences in terms of loss of QoL following injury in a Swedish population and to investigate the response shift in retrospective measures of self-reported QoL.
We will analyse preinjury and postinjury (including both minor and severe unintentional injuries as well as different injury mechanisms) assessments of QoL, including the phenomenon of response shift, using register-based data from the nationwide collaboration project LifeGene, which includes over 52 000 individuals living in Sweden. In addition to LifeGene data, a short online survey including a 'ThenTest' questionnaire, that is, comparison of previous QoL to current using EuroQoL five-dimensional questionnaire, was sent out to the participants of LifeGene. This study will provide a unique opportunity to study the changes in QoL by comparing preinjury and postinjury assessments using a prospective appraisal, both for populations who have sought medical care as well as those who have not due to their injury. Similarly, the study will also assess the response shift in retrospective measures of QoL. This information can guide the next generation of QoL measures and interventions for those suffering injuries and have an impact on how to interpret evaluations of interventions.
The study has been reviewed and approved by the Regional Ethical Review Board in Stockholm, Sweden (case number 2018/352-31). The results will be disseminated through peer-reviewed journals, conference presentations, print media and internet and via a report for the funding agency.
目前，基于前瞻性评估的、关于损伤前和损伤后生活质量（QoL）评估的研究非常少；特别是，对于受伤后不寻求医疗的人群，相关知识还存在空白。为了填补这些知识空白，本研究旨在确定瑞典人群中受伤后生活质量丧失的心理社会后果，并研究自我报告的 QoL 回顾性测量中的反应转移现象。
我们将使用来自全国性合作项目 LifeGene 的基于登记的资料来分析损伤前和损伤后的 QoL 评估，包括反应转移现象，该项目包括生活在瑞典的 52000 多人。除了 LifeGene 的资料外，还向 LifeGene 的参与者发送了一项简短的在线调查，包括“ThenTest”问卷，即使用 EuroQoL 五维问卷对以前的 QoL 与当前的 QoL 进行比较。本研究将提供一个独特的机会，通过使用前瞻性评估来比较损伤前和损伤后的 QoL 评估，以研究 QoL 的变化，既包括寻求医疗的人群，也包括因受伤而未寻求医疗的人群。同样，该研究还将评估 QoL 回顾性测量中的反应转移现象。这些信息可以为受伤人群的下一代 QoL 测量和干预措施提供指导，并影响对干预措施评估的解释。
该研究已由瑞典斯德哥尔摩地区伦理审查委员会（注册号 2018/352-31）审查和批准。研究结果将通过同行评议的期刊、会议演讲、印刷媒体和互联网以及为资助机构编写的报告进行传播。
