Institute for Diagnostic and Interventional Radiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Institute for Diagnostic and Interventional Radiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Clin Radiol. 2019 Nov;74(11):899.e7-899.e12. doi: 10.1016/j.crad.2019.07.022. Epub 2019 Sep 6.
To evaluate the clinical utility of computed tomography (CT)-guided percutaneous biopsies of suspect pancreatic lesions regarding safety, efficiency, radiation dose, intervention time, diagnostic yield, and complications.
Between 2015 and 2018, 48 patients (18 female, 30 male; mean age: 64.2 years) with suspect pancreatic lesions underwent CT-guided percutaneous biopsy. Ultrasound-guided biopsy of all lesions was not possible or without any result. CT-guided interventions were compared according to the following intervention parameters: radiation dose, procedure duration, number of needle correction scans. Evaluation criteria included technical success as well as major and minor complications according to the Society of Interventional Radiology.
Biopsies were performed successfully in 100% of patients. No major side effects occurred during intervention. As a minor complication, 29.2% showed focal haemorrhage. Seventy-seven percent of lesions had a malignant appearance, and benign inflammatory lesions were found in 23%. The mean size of the target lesions was 2.9 cm (range: 0.7-2.3 cm). The mean target access path within the patient was 8 cm (range: 3-14 cm). The duration to completion was 12 minutes (range: 3 minutes 30 seconds to 30 minutes). The dose-length product of the intervention was 89.5 mGy·cm (range: 11-350 mGy·cm). The average number needle correction scans was 31.1 (range: 6-36).
CT-guided biopsy of suspect pancreatic lesions is an efficient and safe method. It can be performed within short intervention times and low radiation exposure for differentiation of unclear lesions.
评估计算机断层扫描（CT）引导下经皮穿刺活检可疑胰腺病变的临床实用性，包括安全性、效率、辐射剂量、介入时间、诊断率和并发症。
2015 年至 2018 年间，48 例可疑胰腺病变患者（18 例女性，30 例男性；平均年龄：64.2 岁）接受了 CT 引导下经皮穿刺活检。所有病变均无法进行或无超声引导活检结果。根据以下介入参数比较 CT 引导下的介入：辐射剂量、手术时间、针校正扫描次数。评估标准包括技术成功率以及根据介入放射学会的主要和次要并发症。
所有患者均成功进行了活检。介入过程中未发生重大副作用。作为一种轻微并发症，29.2%的患者出现局灶性出血。77%的病变表现为恶性，23%为良性炎症性病变。靶病变的平均大小为 2.9 厘米（范围：0.7-2.3 厘米）。患者内的平均目标进入路径为 8 厘米（范围：3-14 厘米）。完成手术的时间为 12 分钟（范围：3 分 30 秒至 30 分钟）。介入的剂量长度乘积为 89.5 mGy·cm（范围：11-350 mGy·cm）。平均针校正扫描次数为 31.1 次（范围：6-36 次）。
CT 引导下活检可疑胰腺病变是一种高效、安全的方法。对于区分不明原因的病变，它可以在短时间的介入和低辐射暴露下进行。
