De Bastiani Maiby, Ribeiro Caroline Kullmann, Rech Bruna, Cartell André, Escobar Gabriela Fortes
University of Rio Grande do Sul Medical School, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Private Practice, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Skinmed. 2019 Sep 9;17(3):200-202. eCollection 2019.
A 32-year-old man presented to the dermatology department with generalized asymptomatic yellowish papules on an erythematous base, arms, thighs, and buttocks. These lesions had appeared in the previous month (Figure 1). Dermoscopy revealed a homogeneous yellow color, corresponding to dermal xanthomatous deposits, with interconnected fine and dotted vessels (Figure 2). The laboratory findings showed extremely high levels of triglycerides (4.842 mg/dL; normal <150), as well as increased total cholesterol (576 mg/dL; normal <200), fasting blood glucose (294 mg/dL), and glycated hemoglobin 12.3% (normal range 4% to 6%). A skin biopsy demonstrated foamy cells, with extracellular lipid between collagen bundles in the dermis (Figure 3).
一名32岁男性因手臂、大腿和臀部出现以红斑为基底的全身性无症状淡黄色丘疹而就诊于皮肤科。这些皮疹于前一个月出现（图1）。皮肤镜检查显示均匀的黄色，对应真皮内的黄色瘤沉积，伴有相互连接的细点状血管（图2）。实验室检查结果显示甘油三酯水平极高（4.842 mg/dL；正常<150），总胆固醇升高（576 mg/dL；正常<200），空腹血糖（294 mg/dL），糖化血红蛋白12.3%（正常范围4%至6%）。皮肤活检显示有泡沫细胞，真皮内胶原束之间有细胞外脂质（图3）。
