Suneetha K P, Gudaganatti Sunil Basappa, Gayathri J
Department of Pathology, Apollo Hospital, Sheshadripuram, New No 1, Old no 28, Platform Road, Bangalore, Karnataka 560020 India.
Indian J Surg Oncol. 2019 Sep;10(3):540-541. doi: 10.1007/s13193-019-00939-0. Epub 2019 Jun 5.
Leiomyosarcoma (LMS) of vascular origin is uncommon. This leiomyosarcoma is seen occurring from the tunica media of major blood vessels. Leiomyosarcoma of venous origin is five times more common those of arterial origin. Most cases are presented in woman with a median age of 50 years [1]. We are presenting a case where histopathology was instrumental in making the diagnosis of LMS in the thrombus and confirmed by IHC. A 46-year old female presented with bilateral swelling of lower limbs and distention of abdomen. Her CT, MRI, and color Doppler were suggestive of IVC, hepatic, and renal vein thrombosis. Histopathology of thrombus revealed leiomyosarcoma and was confirmed by IHC. Conservative treatment was given and asked for a regular follow-up. This case report gives us an opportunity to think of a differential diagnosis in a patient presenting with IVC thrombus.
血管源性平滑肌肉瘤（LMS）并不常见。这种平滑肌肉瘤可见于主要血管的中膜。静脉源性平滑肌肉瘤比动脉源性平滑肌肉瘤常见五倍。大多数病例发生在女性，中位年龄为50岁[1]。我们现报告一例，其中组织病理学有助于诊断血栓中的LMS，并经免疫组化证实。一名46岁女性出现双下肢肿胀和腹部膨隆。她的CT、MRI和彩色多普勒检查提示下腔静脉、肝静脉和肾静脉血栓形成。血栓的组织病理学显示为平滑肌肉瘤，并经免疫组化证实。给予了保守治疗并要求定期随访。本病例报告让我们有机会思考一名出现下腔静脉血栓患者的鉴别诊断。
