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皮下电流分流在青蛙再生失败中的作用。

Role of subdermal current shunts in the failure of frogs to regenerate.

作者信息

Borgens R B, Vanable J W, Jaffe L F

出版信息

J Exp Zool. 1979 Jul;209(1):49-56. doi: 10.1002/jez.1402090106.

DOI:10.1002/jez.1402090106
PMID:314968
Abstract

Large, uniform, skin-driven currents (20-40 muamp/cm2) leave the ends of limb stumps of post-metamorphic frogs (Rana pipiens) from about the first through the tenth day after amputation. However, right after amputation, while currents of comparable density may leave the periphery of the cut surface, current densities are greatly depressed in the center of this surface. We suggest that this depression is brought about by shunting through the subdermal lymph space (characteristic of anurans but not urodeles); continues in covert form after formation of a wound epithelium; and helps explain the ability of small, imposed currents to initiate frog limb regeneration.

摘要

在截肢后的大约第一天到第十天,大的、均匀的、由皮肤驱动的电流(20 - 40微安/平方厘米)从变态后的青蛙(豹蛙)肢体残端流出。然而,在截肢后即刻,虽然密度相当的电流可能从切割表面的周边流出,但该表面中心的电流密度却大幅降低。我们认为这种降低是通过皮下淋巴间隙分流造成的(这是无尾目动物而非有尾目动物的特征);在伤口上皮形成后以隐蔽的形式持续存在;并且有助于解释施加的小电流启动青蛙肢体再生的能力。

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Role of subdermal current shunts in the failure of frogs to regenerate.皮下电流分流在青蛙再生失败中的作用。
J Exp Zool. 1979 Jul;209(1):49-56. doi: 10.1002/jez.1402090106.
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