Duy Phan Q, Sreekrishnan Anirudh, David Wyatt, Paranjpe Manish D, Paranjpe Ishan, Sheth Amar, Gültekin Batur, Sheth Kevin N
Medical Scientist Training Program, Yale University School of Medicine, New Haven, CT, USA.
Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Transl Neurosci. 2019 Aug 20;10:233-234. doi: 10.1515/tnsci-2019-0037. eCollection 2019.
Timely dissemination of results from clinical studies is crucial for the advancement of knowledge and clinical decision making. A large body of research has shown that up to half of clinical trials do not publish their findings. In this study, we sought to determine whether clinical trial publication rates within neurology have increased over time. Focusing on neurology clinical trials completed between 2008 to 2014, we found that while the overall percentage of published trials has not changed (remaining at approximately 50%), time to publication has significantly decreased. Our findings suggest that clinical trials within neurology are being published in a more timely manner.
及时传播临床研究结果对于知识进步和临床决策至关重要。大量研究表明,高达一半的临床试验未发表其研究结果。在本研究中,我们试图确定神经病学领域的临床试验发表率是否随时间有所增加。聚焦于2008年至2014年完成的神经病学临床试验,我们发现虽然已发表试验的总体百分比没有变化(仍约为50%),但发表时间显著缩短。我们的研究结果表明,神经病学领域的临床试验正在更及时地发表。