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肝内胆管癌患者的放射回忆反应:病例报告及文献综述

Radiation Recall in a Patient with Intrahepatic Cholangiocarcinoma: Case Report and a Literature Review.

作者信息

Bahaj Waled, Ya'qoub Lina, Toor Muhammad, Masood Ashiq

机构信息

Internal Medicine, University of Missouri-Kansas City School of Medicine, Kansas City, USA.

Oncology, University of Missouri-Kansas City School of Medicine, Kansas City, USA.

出版信息

Cureus. 2019 Jun 27;11(6):e5020. doi: 10.7759/cureus.5020.

DOI:10.7759/cureus.5020
PMID:31497449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6716758/
Abstract

Radiation recall dermatitis (RRD) is a rare and poorly understood phenomenon, constituting an inflammatory skin reaction to a previously irradiated area of skin following the administration of certain agents, usually chemotherapy. Our patient developed RRD 66 years after receiving radiation therapy; to the best of our knowledge, this is the longest reported period in the literature. The mainstay of therapy is to withhold the agent that elicited the adverse reaction, followed by symptomatic management. Subjecting patients to further chemotherapy can provoke another episode of RRD. Therefore, clinical judgment in this regard is usually recommended.

摘要

放射性回忆性皮炎(RRD)是一种罕见且了解甚少的现象,是在给予某些药物(通常是化疗药物)后,对先前接受过放射治疗的皮肤区域产生的炎症性皮肤反应。我们的患者在接受放射治疗66年后发生了RRD;据我们所知,这是文献中报道的最长时间。治疗的主要方法是停用引发不良反应的药物,然后进行对症处理。让患者接受进一步的化疗可能会引发另一轮RRD。因此,通常建议在此方面进行临床判断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/6716758/9f29f28b4599/cureus-0011-00000005020-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/6716758/dffa66e4582d/cureus-0011-00000005020-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/6716758/9f29f28b4599/cureus-0011-00000005020-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/6716758/dffa66e4582d/cureus-0011-00000005020-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0c/6716758/9f29f28b4599/cureus-0011-00000005020-i02.jpg

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本文引用的文献

1
Acute and Chronic Cutaneous Reactions to Ionizing Radiation Therapy.电离辐射治疗的急性和慢性皮肤反应
Dermatol Ther (Heidelb). 2016 Jun;6(2):185-206. doi: 10.1007/s13555-016-0120-y. Epub 2016 Jun 1.
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Radiation recall following cisplatin chemotherapy.顺铂化疗后的放射回忆反应。
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治疗性血液成分单采、循环中的磷脂酶D与皮肤黏膜毒性:我们四年的临床经验
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Lung Cancer. 2006 Dec;54(3):423-5. doi: 10.1016/j.lungcan.2006.06.021. Epub 2006 Oct 17.
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Radiation recall: a well recognized but neglected phenomenon.放射回忆:一种广为人知却被忽视的现象。
Cancer Treat Rev. 2005 Nov;31(7):555-70. doi: 10.1016/j.ctrv.2005.07.008. Epub 2005 Sep 15.
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Gemcitabine-induced radiation recall dermatitis in a patient with resistant Hodgkin lymphoma.吉西他滨诱发的放射性回忆性皮炎见于1例难治性霍奇金淋巴瘤患者。
Am J Hematol. 2005 Sep;80(1):91. doi: 10.1002/ajh.20379.
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Radiation-recall skin disorders associated with the use of antineoplastic drugs. Pathogenesis, prevalence, and management.与使用抗肿瘤药物相关的放射性回忆性皮肤病。发病机制、患病率及管理。
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Characterizing the phenomenon of radiation recall dermatitis.描述放射性回忆性皮炎现象。
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