Chen Chengfang, Shi Guanggang, He Mingqiang, Song Xinlei, Cheng Xueqing, Wang Baowei, Gu Hongbo, Liang Xuhui, Yu Shudong
Department of Otorhinolaryngology Head and Neck Surgery, Shandong Provincial Hospital Affiliated to Shandong University , Jinan , China.
Acta Otolaryngol. 2019 Nov;139(11):959-965. doi: 10.1080/00016489.2019.1657589. Epub 2019 Sep 9.
Few studies focused on the prognosis of sudden sensorineural hearing loss (ISSHL) of aged people. The aim of this study is to analyze the characteristics, treatment, and prognostic factors of ISSHL in aged people. A total of 278 patients diagnosed of ISSHL in aged people from 2014 to 2019 were retrospectively analyzed. Univariates were analyzed by univariate and multivariate logistic analysis. Among the 13 univariates, the patients' age was younger in the overall recovery group ORG ( = .018), while onset days was shorter in ORG ( = .000). The percentage of DM and HTN comorbidities were higher in ORG ( = .026 and .038). Meanwhile differences were significant in audiogram configurations ( = .037), the degree of hearing loss ( = .033), and types of lipid treatment ( = .020). Then these seven independent risk factors were included in the multivariate analysis, final results indicated that hypertension ( = .028), lipid control groups ( = .009), age ( = .000), and onset days ( = .001) were related to the treatment outcome of ISSHL. The prognosis of ISSHL in aged patients was closely related to age, the onset days of treatment, and good control of complications such as hypertension and hyperlipidemia, so vascular factors were considered as the main causes of morbidity.
很少有研究关注老年突发性感音神经性听力损失(ISSHL)的预后。本研究旨在分析老年ISSHL的特征、治疗及预后因素。对2014年至2019年诊断为老年ISSHL的278例患者进行回顾性分析。通过单因素和多因素逻辑分析进行单因素分析。在13个单因素中,总体恢复组(ORG)患者年龄较小(P = 0.018),而ORG组的发病天数较短(P = 0.000)。ORG组糖尿病和高血压合并症的百分比更高(P = 0.026和0.038)。同时,听力图形态(P = 0.037)、听力损失程度(P = 0.033)和血脂治疗类型(P = 0.020)存在显著差异。然后将这七个独立危险因素纳入多因素分析,最终结果表明高血压(P = 0.028)、血脂控制组(P = 0.009)、年龄(P = 0.000)和发病天数(P = 0.001)与ISSHL的治疗结果相关。老年患者ISSHL的预后与年龄、治疗发病天数以及高血压和高脂血症等并发症的良好控制密切相关,因此血管因素被认为是发病的主要原因。