日本特发性突发性感音神经性听力损失的全国性流行病学调查。
Nationwide epidemiological survey of idiopathic sudden sensorineural hearing loss in Japan.
作者信息
Kitoh Ryosuke, Nishio Shin-Ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Sone Michihiko, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-Ichi
机构信息
a Department of Otorhinolaryngology , Shinshu University School of Medicine , Matsumoto , Japan.
b Department of Otorhinolaryngology Head and Neck Surgery , Keio University School of Medicine , Tokyo , Japan.
出版信息
Acta Otolaryngol. 2017;137(sup565):S8-S16. doi: 10.1080/00016489.2017.1297537. Epub 2017 Apr 10.
OBJECTIVES
Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan.
METHODS
The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated. Statistical analysis was performed to clarify the factors associated with the severity of hearing impairment and prognosis.
RESULTS
There were significant correlations between the severity of hearing loss and diabetes mellitus, kidney disease, past history of brain infarction, heart disease, age (under 16 years/elderly), and symptoms of vertigo/dizziness. We also analyzed the prognostic factors for idiopathic SSNHL, and found that the severity of hearing loss (Grade 3 or 4), heart disease, aged 65 years or over, time from onset to treatment (over 7 days), and symptoms of vertigo/dizziness were all significantly related to poor prognosis.
CONCLUSION
The present large-scale clinical survey revealed current epidemiological trends for idiopathic sudden sensorineural hearing loss (SSNHL) and various factors associated with the severity of hearing impairment and prognosis.
目的
利用大规模全国性调查数据库，我们调查了日本特发性突发性聋（SSNHL）的流行病学特征。
方法
本分析的对象为2014年4月至2016年3月期间登记在日本多中心数据库中的患者。该数据库共登记了3419例特发性SSNHL患者，并获取了这些患者的临床特征。随后研究了与听力损失严重程度及预后相关的几个因素。进行统计分析以阐明与听力损失严重程度及预后相关的因素。
结果
听力损失严重程度与糖尿病、肾脏疾病、脑梗死病史、心脏病、年龄（16岁以下/老年人）以及眩晕/头晕症状之间存在显著相关性。我们还分析了特发性SSNHL的预后因素，发现听力损失严重程度（3级或4级）、心脏病、65岁及以上、发病至治疗时间（超过7天）以及眩晕/头晕症状均与预后不良显著相关。
结论
本次大规模临床调查揭示了特发性突发性感音神经性听力损失（SSNHL）的当前流行病学趋势以及与听力损失严重程度和预后相关的各种因素。
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