Hosa Hanna, Bueter Marco
Bariatrische und Endokrine Chirurgie, Universitätsspital Zürich.
Ther Umsch. 2019 Sep;76(3):123-127. doi: 10.1024/0040-5930/a001072.
Mechanisms of bariatric and metabolic surgery Abstract: Under the circumstances of rising numbers of patients suffering obesity and its related comorbidities, bariatric -surgery becomes a more and more important treatment option. Thereby the Roux-en-Y gastric bypass (= RYGB) and sleeve gastrectomy (= SG) are the most frequent operations performed in this field. The significant weight loss and the observed changes in food consumption cannot be explained by mechanical restriction and caloric malabsorption as initially assumed, but seem to be rather based on a complex interplay of endocrinological, neurological and behavioral mechanisms. It is thus the aim of this article to provide a short overview on the most important physiological mechanisms of bariatric and metabolic -surgery considering the available data to date.
减重与代谢手术的机制 摘要：在肥胖及其相关合并症患者数量不断增加的情况下，减重手术成为越来越重要的治疗选择。其中，Roux-en-Y胃旁路术（=RYGB）和袖状胃切除术（=SG）是该领域最常施行的手术。显著的体重减轻以及观察到的食物摄入变化，并非如最初所认为的那样，是由机械性限制和热量吸收不良所导致，而是似乎基于内分泌、神经和行为机制的复杂相互作用。因此，本文旨在根据迄今可得的数据，对减重与代谢手术最重要的生理机制进行简要概述。
