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How else can we approach prostate cancer biomarker discovery?我们还能如何进行前列腺癌生物标志物的发现？
Expert Rev Mol Diagn. 2020 Feb;20(2):123-125. doi: 10.1080/14737159.2019.1665507. Epub 2019 Sep 10.
2
Clinical utility of emerging biomarkers in prostate cancer liquid biopsies.在前列腺癌液体活检中新兴生物标志物的临床应用。
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An evaluation of current prostate cancer diagnostic approaches with emphasis on liquid biopsies and prostate cancer.当前前列腺癌诊断方法的评估，重点是液体活检和前列腺癌。
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Biomarkers in previous histologically negative prostate biopsies can be helpful in repeat biopsy decision-making processes.先前组织学阴性前列腺活检中的生物标志物有助于重复活检决策过程。
Cancer Med. 2020 Oct;9(20):7524-7536. doi: 10.1002/cam4.3419. Epub 2020 Aug 28.
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Prebiopsy multiparametric 3T prostate MRI in patients with elevated PSA, normal digital rectal examination, and no previous biopsy.对前列腺特异抗原（PSA）升高、直肠指检正常且未曾接受过活检的患者进行活检前多参数3T前列腺磁共振成像（MRI）检查。
J Magn Reson Imaging. 2015 May;41(5):1394-404. doi: 10.1002/jmri.24682. Epub 2014 Jun 23.
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J Urol. 2015 Dec;194(6):1601-6. doi: 10.1016/j.juro.2015.06.078. Epub 2015 Jun 19.
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Multiparametric magnetic resonance imaging in the detection of prostate cancer.多参数磁共振成像在前列腺癌检测中的应用
Aktuelle Urol. 2014 Mar;45(2):119-26. doi: 10.1055/s-0034-1371875. Epub 2014 Apr 3.
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Detecting prostate cancer and prostatic calcifications using advanced magnetic resonance imaging.使用先进的磁共振成像检测前列腺癌和前列腺钙化。
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PPP1R14B as a potential biomarker for the identification of diagnosis and prognosis affecting tumor immunity, proliferation and migration in prostate cancer.PPP1R14B作为一种潜在的生物标志物，用于鉴定影响前列腺癌肿瘤免疫、增殖和迁移的诊断及预后。
J Cancer. 2024 Oct 21;15(20):6545-6564. doi: 10.7150/jca.101100. eCollection 2024.
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Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer.前列腺癌高通量数据集中的差异基因表达与加权相关网络动态
Front Oncol. 2022 Jun 1;12:881246. doi: 10.3389/fonc.2022.881246. eCollection 2022.
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Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics.利用脂质组学和转录组学的空间方法解析前列腺癌异质性
Cancers (Basel). 2022 Mar 27;14(7):1702. doi: 10.3390/cancers14071702.
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Fresh tissue procurement and preparation for multicompartment and multimodal analysis of the prostate tumor microenvironment.新鲜组织采集和准备用于前列腺肿瘤微环境的多区室和多模式分析。
Prostate. 2022 May;82(7):836-849. doi: 10.1002/pros.24326. Epub 2022 Feb 28.
5
Applications and continued evolution of glycan imaging mass spectrometry.聚糖成像质谱技术的应用和持续发展。
Mass Spectrom Rev. 2023 Mar;42(2):674-705. doi: 10.1002/mas.21725. Epub 2021 Aug 15.
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Mass Spectrometry Imaging of Fibroblasts: Promise and Challenge.质谱成像技术在成纤维细胞中的应用：前景与挑战。
Expert Rev Proteomics. 2021 Jun;18(6):423-436. doi: 10.1080/14789450.2021.1941893. Epub 2021 Jul 24.
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Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells.聚糖成像质谱：用于组织、生物体液和细胞的临床诊断检测方法的进展。
Clin Lab Med. 2021 Jun;41(2):247-266. doi: 10.1016/j.cll.2021.03.005. Epub 2021 Apr 24.

本文引用的文献

1
Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer.晚期前列腺癌循环生物标志物共识声明
Eur Urol Oncol. 2018 Jun;1(2):151-159. doi: 10.1016/j.euo.2018.02.009. Epub 2018 May 15.
2
Current Status of MRI and PET in the NCCN Guidelines for Prostate Cancer.NCCN 前列腺癌指南中 MRI 和 PET 的现状。
J Natl Compr Canc Netw. 2019 May 1;17(5):506-513. doi: 10.6004/jnccn.2019.7306.
3
Galectins in prostate and bladder cancer: tumorigenic roles and clinical opportunities.半乳糖凝集素在前列腺癌和膀胱癌中的作用：致瘤作用和临床机遇。
Nat Rev Urol. 2019 Jul;16(7):433-445. doi: 10.1038/s41585-019-0183-5.
4
MALDI Mass Spectrometry Imaging of N-Linked Glycans in Tissues.基质辅助激光解吸电离质谱成像技术在组织中 N-连接聚糖的应用
Adv Exp Med Biol. 2018;1104:59-76. doi: 10.1007/978-981-13-2158-0_4.
5
The requirement for immune infiltration and organization in the tumor microenvironment for successful immunotherapy in prostate cancer.前列腺癌免疫治疗中肿瘤微环境对免疫浸润和组织的要求。
Urol Oncol. 2019 Aug;37(8):543-555. doi: 10.1016/j.urolonc.2018.10.011. Epub 2018 Nov 13.
6
Prostate cancer PET tracers: essentials for the urologist.前列腺癌PET示踪剂：泌尿外科医生须知要点
Can J Urol. 2018 Aug;25(4):9371-9383.
7
Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.前列腺癌转录组的空间图谱揭示了一种未被探索的异质性景观。
Nat Commun. 2018 Jun 20;9(1):2419. doi: 10.1038/s41467-018-04724-5.
8
Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis.癌症中的糖基化：在肿瘤进展、免疫调节和转移中的选择作用。
Cell Immunol. 2018 Nov;333:46-57. doi: 10.1016/j.cellimm.2018.03.007. Epub 2018 Mar 20.
9
Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry.基质蛋白在福尔马林固定、石蜡包埋组织中的 MALDI 成像质谱分析。
J Proteome Res. 2018 Jan 5;17(1):635-646. doi: 10.1021/acs.jproteome.7b00713. Epub 2017 Dec 11.
10
Liquid biopsy: a step forward towards precision medicine in urologic malignancies.液体活检：朝着泌尿生殖系统恶性肿瘤精准医学迈进的一步。
Mol Cancer. 2017 Apr 14;16(1):80. doi: 10.1186/s12943-017-0644-5.

How else can we approach prostate cancer biomarker discovery?

作者信息

Drake Richard R, Angel Peggi M, Wu Jennifer, Pachynski Russell K, Ippolito Joseph E

机构信息

Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA.

Departments of Urology and Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Expert Rev Mol Diagn. 2020 Feb;20(2):123-125. doi: 10.1080/14737159.2019.1665507. Epub 2019 Sep 10.

DOI:10.1080/14737159.2019.1665507
PMID:31498690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7035159/
Abstract
摘要