Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea.
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea.
Ann Thorac Surg. 2020 Apr;109(4):1112-1119. doi: 10.1016/j.athoracsur.2019.07.053. Epub 2019 Sep 6.
We have performed off-pump coronary artery bypass grafting and also performed early postoperative angiography to assess anastomosis accuracy and patency in most of our patients requiring surgical revascularization.
Of 3083 patients who underwent isolated coronary artery bypass grafting between 1998 and 2017, 2919 patients (94.7%) underwent off-pump coronary artery bypass grafting. Conduits for distal anastomoses were left internal thoracic artery (n = 2764), right internal thoracic artery (n = 866), right gastroepiploic artery (n = 997), radial artery (n = 16), and saphenous vein (n = 1505). Since the introduction of transit-time flow measurement in 2000, we revised abnormal grafts intraoperatively. Early (≤7 days) angiography was performed in 2820 patients (96.6%) at 1.5 ± 1.2 postoperative days, and surgical intervention was performed based on angiographic findings.
Operative mortality was 1.1% (32 of 2919). Average number of distal anastomoses was 3.2 ± 1.0. Intraoperative flowmetry-guided revision for distal anastomosis failures was performed in 109 of 8585 distal anastomoses (1.3%). Angiography showed an overall patency of 98.2% (8836 of 9001): 99.0% (5484 of 5540) for arterial and 96.9% (3352 of 3461) for venous conduits (P < .001). Patency of venous conduits was 87.2% (231 of 265) for free grafts and 97.7% (3121 of 3196) for composite grafts (P = .001). After the introduction of transit-time flow measurement, patency of arterial conduits became significantly higher (97.2% vs 99.2%; P = .038); however, patency of free venous conduits was not significantly improved (86.0% vs 91.4%; P = .181). Early re-intervention according to angiographic findings was performed in 76 patients (2.7%). Reevaluation of graft patency before discharge in 31 who underwent revision of distal anastomoses showed improved patency (65.1% [56 of 86] vs 95.3% [82 of 86]; P < .001).
Intraoperative flowmetry and revision of abnormal grafts improved early arterial graft patency, and reoperation based on early angiographic findings may further improve graft patency at the time of discharge.
我们已经进行了非体外循环冠状动脉旁路移植术,并在大多数需要手术血运重建的患者中进行了术后早期血管造影术,以评估吻合口的准确性和通畅性。
在 1998 年至 2017 年间接受单纯冠状动脉旁路移植术的 3083 例患者中,2919 例(94.7%)接受了非体外循环冠状动脉旁路移植术。远端吻合的移植物为左内乳动脉(n=2764)、右内乳动脉(n=866)、右胃网膜动脉(n=997)、桡动脉(n=16)和大隐静脉(n=1505)。自 2000 年引入渡越时间流量测量以来,我们在术中对异常移植物进行了修正。在 2820 例患者(96.6%)中,术后 1.5±1.2 天进行了早期(≤7 天)血管造影术,并根据血管造影结果进行了手术干预。
手术死亡率为 1.1%(32/2919)。平均远端吻合口数为 3.2±1.0。术中流量测量引导的 8585 个远端吻合口中的 109 个(1.3%)发生吻合口失败。造影显示总通畅率为 98.2%(8836/9001):动脉通畅率为 99.0%(5484/5540),静脉通畅率为 96.9%(3352/3461)(P<.001)。静脉移植物的通畅率为游离移植物 87.2%(231/265),复合移植物 97.7%(3121/3196)(P=.001)。在引入渡越时间流量测量后,动脉移植物的通畅率显著提高(97.2%比 99.2%;P=.038);然而,游离静脉移植物的通畅率并未显著改善(86.0%比 91.4%;P=.181)。根据血管造影结果,76 例患者(2.7%)进行了早期再干预。31 例远端吻合口修正患者在出院前进行了再次评估,显示通畅率改善(65.1%[56/86]比 95.3%[82/86];P<.001)。
术中流量测量和异常移植物的修正改善了早期动脉移植物通畅率,根据早期血管造影结果进行再次手术可能会进一步提高出院时移植物的通畅率。