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内镜下静脉采集

Endoscopic vein harvesting.

作者信息

Akowuah Enoch, Burns Daniel, Zacharias Joseph, Kirmani Bilal H

机构信息

Department of Cardiac Surgery, James Cook University Hospital, South Tees NHS, Foundation Trust, Middlesbrough, UK.

Department of Cardiac Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.

出版信息

J Thorac Dis. 2021 Mar;13(3):1899-1908. doi: 10.21037/jtd-20-1819.

Abstract

Coronary artery bypass grafting is the most common cardiac surgical procedure performed worldwide and the long saphenous vein the most common conduit for this. When performed as an open vein harvest (OVH), the incision on each leg can be up to 85cm long, making it the longest incision of any routine procedure. This confers a high degree of morbidity to the procedure. Endoscopic vein harvest (EVH) methods were popularised over two decades ago, demonstrating significant benefits over OVH in terms of leg wound complications including surgical site infections. They also appeared to hasten return to usual activities and wound healing and became popular particularly in North America. Subgroup analyses of two trials designed for other purposes created a period of uncertainty between 2009-2013 while the impact of endoscopic vein harvesting on vein graft patency and major adverse cardiac events was scrutinised. Large observational studies debunked the findings of increased mortality in the short-term, allowing practitioners and governing bodies to regain some confidence in the procedure. A well designed, adequately powered, randomised controlled trial published in 2019 also definitively demonstrated that there was no increase in death, myocardial infarction or repeat revascularisation with endoscopic vein harvest. Endoscopic vein harvest is a Class IIa indication in European Association of Cardio-Thoracic Surgery (EACTS) and a Class I indication in International Society of Minimally Invasive Cardiac Surgery (ISMICS) guidelines.

摘要

冠状动脉搭桥术是全球最常见的心脏外科手术,而大隐静脉是该手术最常用的血管移植物。当采用开放式静脉采集(OVH)时,每条腿上的切口可达85厘米长,使其成为所有常规手术中最长的切口。这导致该手术具有较高的发病率。二十多年前,内镜下静脉采集(EVH)方法开始普及,在腿部伤口并发症(包括手术部位感染)方面显示出比OVH有显著优势。它们似乎还能加速恢复日常活动和伤口愈合,尤其在北美地区变得流行起来。两项为其他目的设计的试验的亚组分析在2009年至2013年期间造成了一段不确定性,当时对内镜下静脉采集对静脉移植物通畅率和主要不良心脏事件的影响进行了仔细审查。大型观察性研究驳斥了短期内死亡率增加的研究结果,使从业者和管理机构对该手术重新获得了一些信心。2019年发表的一项设计良好、样本量充足的随机对照试验也明确表明,内镜下静脉采集不会增加死亡、心肌梗死或再次血运重建的风险。内镜下静脉采集在欧洲心胸外科学会(EACTS)指南中是IIa类适应证,在国际微创心脏外科学会(ISMICS)指南中是I类适应证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ec7/8024854/7d9e36392c21/jtd-13-03-1899-f1.jpg

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