College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
College of Biomedical Engineering, Capital Medical University, Beijing 100069, China.
Math Biosci Eng. 2019 May 29;16(5):4846-4872. doi: 10.3934/mbe.2019244.
Radiofrequency ablation (RFA) and microwave ablation (MWA) have become an important means for treating liver tumors. RFA and MWA are a minimally invasive therapy which involves an ablation applicator or needle (i.e., radiofrequency electrode or microwave antenna) inserted percutaneously into a tumor under the guidance of medical imaging, so as to destroy the tumor in situ by heating-induced coagulation necrosis. Treatment planning, particularly needle trajectory planning, is crucial to RFA and MWA. In clinical procedures, however, needle trajectory planning still relies on the personal experience of clinicians. Manual needle trajectory planning is tedious and may cause inter-operator difference. Therefore, computer-assisted needle trajectory planning techniques are of clinical value and have been extensively explored. However, a literature review that focuses on computer-assisted needle trajectory planning for liver tumor RFA and MWA has not been reported. In this paper, we conducted an extensive review on computer-assisted needle trajectory planning for RFA and MWA of liver tumors. Fundamentals of needle trajectory planning are summarized. Algorithms for single-needle and multi-needle trajectory planning are analyzed. Shortcomings of current computer-assisted needle trajectory planning algorithms are discussed and future developments are suggested.
射频消融（RFA）和微波消融（MWA）已成为治疗肝肿瘤的重要手段。RFA 和 MWA 是一种微创治疗方法，在医学影像的引导下，经皮将消融器械或针（即射频电极或微波天线）插入肿瘤内，通过热诱导凝固性坏死原位破坏肿瘤。治疗计划，特别是针道规划，对于 RFA 和 MWA 至关重要。然而，在临床操作中，针道规划仍然依赖于临床医生的个人经验。手动针道规划繁琐，可能导致操作者之间的差异。因此，计算机辅助针道规划技术具有临床价值，并得到了广泛的探索。然而，目前尚未有专门针对肝肿瘤 RFA 和 MWA 的计算机辅助针道规划的文献综述。本文对肝肿瘤 RFA 和 MWA 的计算机辅助针道规划进行了广泛的综述。总结了针道规划的基本原理。分析了单针和多针轨迹规划的算法。讨论了当前计算机辅助针道规划算法的不足之处，并提出了未来的发展方向。
