Arrhythmology Unit, San Raffaele Hospital, Milan, Italy (K.O, A.F., C.B., G.P., A.R., L.F., P.D.B.).
Abbott Medical Italy, Sesto San Giovanni, Milano, Italy (F.C).
Circ Arrhythm Electrophysiol. 2019 Sep;12(9):e007500. doi: 10.1161/CIRCEP.119.007500. Epub 2019 Sep 10.
A new grid mapping catheter (GMC)-allowing for bipolar recordings of the electrograms in each orthogonal direction-became available. The aim of the current study is to evaluate the utility of the GMC in creating substrate and ventricular tachycardia (VT) activation maps during VT ablation procedures.
From December 2017 to July 2018, 41 consecutive patients undergoing a VT ablation procedure using a GMC were studied. During the substrate mapping, 3 different maps were created using the 3 GMC bipolar configurations (along the spline, across the spline, HD wave solution); the low voltage area and late potential areas were compared. In case of inducible VTs, the GMC was used to create the VT activation maps focusing on the diastolic interval. The relation between diastolic activities during VT and substrate abnormality during sinus rhythm was also investigated.
The median low-voltage area drawn by the HD wave configuration was 28.9 cm, 13% and 15% smaller than the low-voltage areas identified by the along and across configuration, respectively (33.1 and 33.9 cm; P<0.0001). The late potential areas obtained with the 3 GMC configuration did not differ (P>0.05). VT activation mappings using the GMC were performed in 40 VTs, visualizing the full diastolic pathway in 22 (55%) of them. While the latest late potential areas were included in VT diastolic pathway in 17 VTs, the other 6 VTs showed mismatching of them. Identifying the full diastolic pathway led to a higher ongoing VT termination rate during the ablation than in case of partial recordings (88% versus 45%; P=0.03); furthermore, in the former situation, the noninducibility of the targeted VTs was achieved in all cases.
The GMC is a useful tool for performing substrate and VT activation mappings during the VT ablation procedure, precisely identifying the low-voltage areas and quickly visualizing the diastolic pathways.
一种新的栅格标测导管(GMC)可实现每个正交方向的双极电图记录,现已投入使用。本研究旨在评估 GMC 在 VT 消融过程中创建基质和室性心动过速(VT)激活图的效用。
2017 年 12 月至 2018 年 7 月,连续 41 例接受 GMC 引导的 VT 消融术的患者入组。在基质标测过程中,使用 3 种 GMC 双极构形(沿样条、跨样条、HD 波解)创建 3 种不同的图;比较低电压区和晚期电位区。对于可诱导的 VT,使用 GMC 创建 VT 激活图,重点关注舒张期间隔。还研究了 VT 期间的舒张活动与窦性节律期间基质异常之间的关系。
HD 波构形绘制的中位数低电压区为 28.9cm,比沿样条和跨样条构形分别小 13%和 15%(33.1cm 和 33.9cm;P<0.0001)。3 种 GMC 构形获得的晚期电位区无差异(P>0.05)。使用 GMC 进行了 40 次 VT 激活标测,其中 22 次(55%)可见完整的舒张通路。虽然 17 次 VT 中的最晚晚期电位区包括在 VT 舒张通路中,但另外 6 次 VT 显示出不匹配。识别完整的舒张通路可提高消融期间持续性 VT 终止率(88%比 45%;P=0.03);此外,在前一种情况下,所有情况下均实现了靶向 VT 的非诱发性。
GMC 是在 VT 消融过程中进行基质和 VT 激活标测的有用工具,可准确识别低电压区并快速可视化舒张通路。