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一种源自小鼠X射线诱导胸腺瘤的新型GD1c神经节苷脂IV3(NeuAcα2-8 NeuGc)Gg4Cer。

A novel form of GD1c ganglioside IV3 (NeuAc alpha 2-8 NeuGc)Gg4Cer from murine X-ray induced thymoma.

作者信息

Pacuszka T, Antoniewicz J

机构信息

Department of Biochemistry, Institute of Hematology, Warszawa, Poland.

出版信息

Acta Biochim Pol. 1988;35(4):387-93.

PMID:3150198
Abstract

Four disialoganglioside fractions were isolated from X-ray induced thymoma in C57Bl/6 mice. On the basis of compositional and methylation analyses as well as degradation with specific exoglycosidases a novel form of GD1c ganglioside NeuAc alpha 2-8 NeuGc alpha 2-3 Gal beta 1-3 GalNAc beta 1-4 Gal beta 1-4 GlcCer was identified.

摘要

从C57Bl/6小鼠的X射线诱导胸腺瘤中分离出四个双唾液酸神经节苷脂组分。基于组成分析、甲基化分析以及用特定外切糖苷酶降解,鉴定出一种新型的GD1c神经节苷脂NeuAcα2-8NeuGcα2-3Galβ1-3GalNAcβ1-4Galβ1-4GlcCer。

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