Phenytoin-induced thrombocytopenia.
作者信息
Brown J J, Chun R W
机构信息
Department of Neurology, University of Wisconsin School of Medicine, Madison 53792.
出版信息
Pediatr Neurol. 1986 Mar-Apr;2(2):99-101. doi: 10.1016/0887-8994(86)90064-0.
PMID:3150279
Abstract
A 15-year-old boy developed thrombocytopenia and purpura two weeks after starting phenytoin therapy. The blood phenytoin level was in the toxic range. There was an increase in immature neutrophils but no abnormalities were present in other cell lines. Recovery was complete after drug therapy was discontinued. Thrombocytopenia is a rare isolated complication of phenytoin therapy. The probable autoimmune etiology distinguishes this syndrome from other phenytoin-induced blood dyscrasias.
摘要
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