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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Bjare U, Lundblad G, Ivhed I, Nilsson K

National Bacteriological Laboratory, Stockholm, Sweden.

Int J Biochem. 1988;20(11):1291-8. doi: 10.1016/0020-711x(88)90234-0.

The cell bound glycosidases in sublines and clones of the histiocytic cell line U-937 have previously been shown to display characteristic patterns. 2. In this paper the effects of differentiation inducing agents upon glycosidase patterns of one subline, U-937 GTB, are presented. 3. Teleocidin, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), dimethyl-sulfoxide (DMSO), dihydroxyvitamin D3 and supernatants from mixed lymphocyte culture (MCL) all induce cellular differentiation of U-937 GTB. 4. Significant changes of the levels of cell bound glycosidases were seen after addition of inducing agents. 5. Alterations have been monitored as relative effects upon the absolute glycosidase activities and as effects upon selected ratios of different glycosidases. 6. The separate inducing agents show distinct enzyme patterns.

组织细胞系U-937的亚系和克隆中的细胞结合糖苷酶先前已显示出特征性模式。2. 本文介绍了分化诱导剂对一个亚系U-937 GTB糖苷酶模式的影响。3. 远藤菌素、12-O-十四酰佛波醇-13-乙酸酯（TPA）、二甲基亚砜（DMSO）、二羟基维生素D3和混合淋巴细胞培养物（MCL）的上清液均能诱导U-937 GTB细胞分化。4. 添加诱导剂后，细胞结合糖苷酶水平出现显著变化。5. 已将变化监测为对绝对糖苷酶活性的相对影响以及对不同糖苷酶选定比率的影响。6. 单独的诱导剂显示出不同的酶模式。

Bjare U, Lundblad G, Ivhed I, Nilsson K

National Bacteriological Laboratory, Stockholm, Sweden.

Int J Biochem. 1988;20(11):1291-8. doi: 10.1016/0020-711x(88)90234-0.

The cell bound glycosidases in sublines and clones of the histiocytic cell line U-937 have previously been shown to display characteristic patterns. 2. In this paper the effects of differentiation inducing agents upon glycosidase patterns of one subline, U-937 GTB, are presented. 3. Teleocidin, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), dimethyl-sulfoxide (DMSO), dihydroxyvitamin D3 and supernatants from mixed lymphocyte culture (MCL) all induce cellular differentiation of U-937 GTB. 4. Significant changes of the levels of cell bound glycosidases were seen after addition of inducing agents. 5. Alterations have been monitored as relative effects upon the absolute glycosidase activities and as effects upon selected ratios of different glycosidases. 6. The separate inducing agents show distinct enzyme patterns.

组织细胞系U-937的亚系和克隆中的细胞结合糖苷酶先前已显示出特征性模式。2. 本文介绍了分化诱导剂对一个亚系U-937 GTB糖苷酶模式的影响。3. 远藤菌素、12-O-十四酰佛波醇-13-乙酸酯（TPA）、二甲基亚砜（DMSO）、二羟基维生素D3和混合淋巴细胞培养物（MCL）的上清液均能诱导U-937 GTB细胞分化。4. 添加诱导剂后，细胞结合糖苷酶水平出现显著变化。5. 已将变化监测为对绝对糖苷酶活性的相对影响以及对不同糖苷酶选定比率的影响。6. 单独的诱导剂显示出不同的酶模式。