Ijaduola G T, Ademiluyi S A, Olaloye O A, Olarewaju D A
J Natl Med Assoc. 1988 Nov;80(11):1205-7.
A study of axial and peripheral skeletal features of von Recklinghausen's disease in 26 Nigerian African adults has been carried out. Widened intervertebral foramina were the commonest lesions in the axial skeleton of these patients. They occurred in 24 (92.30 percent) of all cervical vertebrae; 20 (76.92 percent) of all lumbar vertebrae; and 16 (61.53 percent) of all thoracic vertebrae. Six (23.08 percent) had lumbar scoliosis. Dysplastic pedicles appeared in 4 (14.38 percent). Malignant changes with bony erosion occurred in two (7.69 percent). Dumbbell features of intraspinal involvement were observed in one patient. It is suggested that in view of the protean nature of presentation of this disease, physicians should always bear it in mind in cases of unusual skeletal lesions and watch carefully for its identifying signs.
对26名尼日利亚成年非洲人进行了冯·雷克林豪森病的轴向和周围骨骼特征研究。椎间孔增宽是这些患者轴向骨骼中最常见的病变。它们出现在所有颈椎的24个（92.30%）；所有腰椎的20个（76.92%）；以及所有胸椎的16个（61.53%）。6名（23.08%）有腰椎侧弯。发育异常的椎弓根出现在4名（14.38%）患者中。发生骨质侵蚀的恶性变化有2名（7.69%）。在1例患者中观察到脊髓内受累的哑铃状特征。建议鉴于该疾病表现形式的多样性，医生在遇到不寻常的骨骼病变时应始终牢记该疾病，并仔细观察其识别体征。
