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STAG Mutations in Cancer.
Trends Cancer. 2019 Aug;5(8):506-520. doi: 10.1016/j.trecan.2019.07.001. Epub 2019 Jul 31.
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LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
Oncogene. 2019 Oct;38(41):6770-6780. doi: 10.1038/s41388-019-0918-z. Epub 2019 Aug 7.
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A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.
Nucleic Acids Res. 2019 Oct 10;47(18):9557-9572. doi: 10.1093/nar/gkz675.
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Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture.
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Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through .
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A functional variant in the boundary of a topological association domain is associated with pancreatic cancer risk.
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WashU Epigenome Browser update 2019.
Nucleic Acids Res. 2019 Jul 2;47(W1):W158-W165. doi: 10.1093/nar/gkz348.
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Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping.
Nucleic Acids Res. 2019 Jul 26;47(13):6699-6713. doi: 10.1093/nar/gkz462.
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A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers.
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An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis.
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