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WashU Epigenome Browser 更新 2019.

WashU Epigenome Browser update 2019.

机构信息

Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

Nucleic Acids Res. 2019 Jul 2;47(W1):W158-W165. doi: 10.1093/nar/gkz348.

DOI:10.1093/nar/gkz348
PMID:31165883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6602459/
Abstract

The WashU Epigenome Browser (https://epigenomegateway.wustl.edu/) provides visualization, integration and analysis tools for epigenomic datasets. Since 2010, it has provided the scientific community with data from large consortia including the Roadmap Epigenomics and the ENCODE projects. Recently, we refactored the codebase, redesigned the user interface, and developed various novel features. New features include: (i) visualization using virtual reality (VR), which has implications in biology education and the study of 3D chromatin structure; (ii) expanded public data hubs, including data from the 4DN, ENCODE, Roadmap Epigenomics, TaRGET, IHEC and TCGA consortia; (iii) a more responsive user interface; (iv) a history of interactions, which enables undo and redo; (v) a feature we call Live Browsing, which allows multiple users to collaborate remotely on the same session; (vi) the ability to visualize local tracks and data hubs. Amazon Web Services also hosts the redesign at https://epigenomegateway.org/.

摘要

华盛顿大学表观基因组浏览器（https://epigenomegateway.wustl.edu/）为表观基因组数据集提供可视化、集成和分析工具。自 2010 年以来，它为科学界提供了来自大型联盟的数据，包括 Roadmap Epigenomics 和 ENCODE 项目。最近，我们重构了代码库，重新设计了用户界面，并开发了各种新功能。新功能包括：（i）使用虚拟现实（VR）进行可视化，这在生物学教育和研究 3D 染色质结构方面具有重要意义；（ii）扩展了公共数据中心，包括来自 4DN、ENCODE、Roadmap Epigenomics、TaRGET、IHEC 和 TCGA 联盟的数据；（iii）更响应式的用户界面；（iv）交互历史记录，支持撤销和重做；（v）我们称之为实时浏览的功能，允许多个用户在同一会话中远程协作；（vi）能够可视化本地轨道和数据中心。亚马逊网络服务（Amazon Web Services）还在 https://epigenomegateway.org/ 上托管了重新设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/f75265f338e1/gkz348fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/9c975d9aea99/gkz348fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/674259aa47e9/gkz348fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/d29f4020058d/gkz348fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/2206ac16f482/gkz348fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/574a84552668/gkz348fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/f75265f338e1/gkz348fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/9c975d9aea99/gkz348fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/674259aa47e9/gkz348fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/d29f4020058d/gkz348fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/2206ac16f482/gkz348fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/574a84552668/gkz348fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fce/6602459/f75265f338e1/gkz348fig6.jpg

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