Shekhtman M M, Glezer G A
Kardiologiia. 1978 Nov;18(11):77-84.
The indices of general hemodynamics and renal function were studied in 362 pregnant women (healthy and those suffering from hypertensive disease, glomerulonephritis or nephropathy) and in 20 healthy but not pregnant women. It was found that the hypokinetic type of circulation developed in glomerulonephritis and nephropathy in pregnant women and that the hyperkinetic type changes to eu- and hypokinetic types in pregnant women suffering from hypertensive disease. In all variants of hypertension in pregnancy, the renal blood flow and glomerular filtration reduce, while the resistance to the blood flow in the vessels of the kidneys increases. The role of the sympathetico-adrenal and the renin-aldosterone systems in the changes in hemodynamics and renal function in healthy and sick pregnant women was studied. An opinion is voiced that increased sensitivity of the vascular receptors to vasoactive substances is very important.
对362名孕妇（包括健康孕妇以及患有高血压疾病、肾小球肾炎或肾病的孕妇）和20名健康未孕女性的一般血液动力学和肾功能指标进行了研究。结果发现，孕妇肾小球肾炎和肾病会出现低动力型循环，而患有高血压疾病的孕妇高动力型循环会转变为正常动力型和低动力型。在妊娠高血压的所有类型中，肾血流量和肾小球滤过率降低，而肾血管血流阻力增加。研究了交感 - 肾上腺系统和肾素 - 血管紧张素 - 醛固酮系统在健康和患病孕妇血液动力学和肾功能变化中的作用。有人认为血管受体对血管活性物质敏感性增加非常重要。
