Urkan M, Peker Y S, Ozturk E
University of Medical Sciences Gulhane Training and Research Hospital - General Surgery, Ankara, Turkey.
Erkan Ozturk Breat and Thyroid Clinic, Ankara, Turkey.
Acta Endocrinol (Buchar). 2019 Apr-Jun;15(2):182-186. doi: 10.4183/aeb.2019.182.
Primary hyperparathyroidism (PHPT), characterized by the inappropriate secretion of parathyroid hormone (PTH) with respect to the extracellular calcium concentration. Curative treatment of PHPT is surgery and bilateral neck exploration has been replaced by minimally invasive parathyroidectomy (MIP), with the advanced imaging technologies combined with radio-guided occult lesion localization (ROLL).
The present study analyzes the MIP data from 45 patients who underwent surgery for parathyroid adenoma and debates if MIP is a feasible technique for the treatment of PHPT.
The study presents the MIP excision data of 45 hyperparathyroidism patients with a 58-month follow up period.
Forty-five operations were performed for 48 parathyroid adenomas. The mean duration of operation was 22.7 (12-55) minutes. Mean follow-up was 14.2 (6-26) months. All patients had normal postoperative calcium levels and PTH levels were normal in the follow-up period, except for one persistent hyperparathyroidism.
ROLL-guided MIP is a feasible technique for parathyroid surgery and reduces surgeon based failure. It also provides the widespread application of parathyroid surgery by decreasing the need for specific experience.
原发性甲状旁腺功能亢进症（PHPT）的特征是甲状旁腺激素（PTH）的分泌相对于细胞外钙浓度而言不适当。PHPT的根治性治疗是手术，双侧颈部探查已被微创甲状旁腺切除术（MIP）所取代，同时结合先进的成像技术与放射性引导隐匿病变定位（ROLL）。
本研究分析了45例行甲状旁腺腺瘤手术患者的MIP数据，并探讨MIP是否是治疗PHPT的可行技术。
该研究展示了45例甲状旁腺功能亢进症患者的MIP切除数据，并进行了58个月的随访。
对48个甲状旁腺腺瘤进行了45次手术。平均手术时长为22.7（12 - 55）分钟。平均随访时间为14.2（6 - 26）个月。所有患者术后钙水平正常，随访期间除1例持续性甲状旁腺功能亢进外，PTH水平均正常。
ROLL引导下的MIP是一种可行的甲状旁腺手术技术，可减少因术者因素导致的失败。它还通过减少对特定经验的需求，促进了甲状旁腺手术的广泛应用。
