种植体周围炎治疗部位微生物群落的变化：一项在比格犬身上的实验研究
Changes of Microbial Community in Treated Peri-implantitis Sites: An Experimental Study in Beagle Dogs.
作者信息
Wu Yu Wei, Zheng Hui, Li Xue Fen, Lu Hui, Lu Song He, Liu Xu Hong, Zeng Qiang, Chen Feng, Lin Jiu Xiang, Tang Zhi Hui
出版信息
Chin J Dent Res. 2019;22(3):165-173. doi: 10.3290/j.cjdr.a43110.
OBJECTIVE
To investigate the changes of the bacterial community in the oral environment of beagle dogs to gain insights on the possible causes of failed therapy in peri-implantitis.
METHODS
Beagles were used as models for experimental peri-implantitis. Samples from peri-implant soft tissue (supramargin and submargin), ligature and contaminated surface of peri-implantitis sites were collected and analysed by sequencing the bacterial 16S rRNA gene.
RESULTS
The residual microbial community from the curettes-treated implant surface contained a variety of microorganisms, including periodontal pathogens, which showed no changes in their composition and structure.
CONCLUSION
It is possible that the residual bacterial community remained unchanged and this was the cause of recurrent episodes of inflammation.
目的
研究比格犬口腔环境中细菌群落的变化，以深入了解种植体周围炎治疗失败的可能原因。
方法
将比格犬作为实验性种植体周围炎的模型。收集种植体周围软组织（龈上和龈下）、结扎线及种植体周围炎部位污染表面的样本，并通过对细菌16S rRNA基因进行测序来分析。
结果
刮治器处理过的种植体表面残留的微生物群落包含多种微生物，包括牙周病原体，其组成和结构未发生变化。
结论
残留细菌群落可能保持不变，这是炎症反复发作的原因。
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