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在一家联邦合格健康中心的丙型肝炎治疗级联反应。

Hepatitis C Treatment Cascade in a Federally Qualified Health Center.

机构信息

Department of Family Medicine, Idaho State University, 921 S. 8th Ave. Stop, Pocatello, ID, 83209, USA.

Department of Psychology, Idaho State University, Pocatello, ID, USA.

出版信息

J Community Health. 2020 Apr;45(2):264-268. doi: 10.1007/s10900-019-00736-4.

Abstract

Hepatitis C (HCV) care cascades have been described in diverse clinical settings, patient populations and countries, highlighting the steps in HCV care where improvements can be made and resources allocated. However, more research is needed to examine barriers to HCV treatment in rural, underserved populations and in Federally Qualified Health Centers (FQHCs). As part of a quality improvement (QI) project, this study aimed to describe and evaluate the HCV treatment cascade in an FQHC serving a large rural patient population in the Western United States. Standardized chart abstraction was utilized to aggregate data regarding patient demographics, the percentage of patients achieving each step in the treatment cascade, and relevant patient (i.e., viral load) and service variables (i.e., whether and when patients received treatment or medication). 389 patients were identified as having HCV and 86% were aware of their diagnosis. Fifty-five percent had their infection confirmed via viral load, 21% were staged for liver disease, 24% received a prescription for treatment, and 19% achieved cure. Compared to national data, the current regional sample had greater rates of diagnosis awareness and access to care, as well as sustained virologic response (SVR), but lower rates of viral load confirmation. Current findings suggest that rural patients living with HCV who receive care at FQHCs struggle to navigate the treatment cascade and achieve a cure, particularly with regard to infection confirmation, liver staging, and prescription. However, compared to national estimates, patients had greater rates of diagnosis awareness/treatment access and SVR.

摘要

丙型肝炎(HCV)护理阶梯已在不同的临床环境、患者群体和国家中进行了描述,突出了可以改进和分配资源的 HCV 护理步骤。然而,需要更多的研究来检查农村、服务不足的人群和联邦合格的健康中心(FQHC)中 HCV 治疗的障碍。作为质量改进(QI)项目的一部分,本研究旨在描述和评估服务于美国西部一个大型农村患者群体的 FQHC 中的 HCV 治疗阶梯。利用标准化图表提取来汇总有关患者人口统计学、治疗阶梯中每个步骤的患者比例以及相关患者(即病毒载量)和服务变量(即患者是否接受治疗或药物以及何时接受治疗或药物)的数据。确定了 389 名患有 HCV 的患者,其中 86%的患者知晓其诊断。55%的患者通过病毒载量确认了感染,21%的患者进行了肝病分期,24%的患者接受了治疗处方,19%的患者获得了治愈。与全国数据相比,当前的区域样本具有更高的诊断意识和获得护理的机会,以及持续病毒学应答(SVR),但病毒载量确认率较低。目前的研究结果表明,在 FQHC 接受治疗的患有 HCV 的农村患者在治疗阶梯中难以获得治愈,特别是在感染确认、肝脏分期和处方方面。然而,与全国估计相比,患者的诊断意识/治疗机会和 SVR 率更高。

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