Patel Priyanka A, Anand Asha S, Parikh Sonia K, Patel Akash D, Kulkarni Rahul S
Department of Medical and Pediatric Oncology, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India.
J Pediatr Neurosci. 2019 Apr-Jun;14(2):86-89. doi: 10.4103/jpn.JPN_81_18.
Burkitt lymphoma is a high-grade B-cell lymphoma with aggressive course of disease and primarily systemic nodal involvement. Primary Burkitt lymphoma with isolated central nervous system (CNS) involvement and that too in pediatric population has been rarely reported. Here, we present a case of a primary Burkitt lymphoma involving brain in an human immunodeficiency virus-positive pediatric patient who was on antiretroviral therapy. Currently, there are no established protocols or guidelines for management of primary CNS Burkitt lymphoma thus posing challenges in the management of such cases. Our patient was successfully treated by surgical resection followed by chemotherapy and radiotherapy.
伯基特淋巴瘤是一种侵袭性病程的高级别B细胞淋巴瘤，主要累及全身淋巴结。原发性伯基特淋巴瘤孤立累及中枢神经系统（CNS），且发生于儿童人群的情况鲜有报道。在此，我们报告一例接受抗逆转录病毒治疗的人类免疫缺陷病毒阳性儿童患者发生原发性伯基特淋巴瘤累及脑部的病例。目前，对于原发性中枢神经系统伯基特淋巴瘤的治疗尚无既定方案或指南，因此此类病例的管理面临挑战。我们的患者通过手术切除，随后进行化疗和放疗，获得了成功治疗。
