• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

股骨头骨骺滑脱和 Blount 病作为早期代谢性手术干预的指标。

Slipped capital femoral epiphysis and Blount disease as indicators for early metabolic surgical intervention.

机构信息

Department of Pediatric Surgery, New York-Presbyterian/Morgan Stanley Children's Hospital, New York, New York.

Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts.

出版信息

Surg Obes Relat Dis. 2019 Oct;15(10):1836-1841. doi: 10.1016/j.soard.2019.06.024. Epub 2019 Jul 2.

DOI:10.1016/j.soard.2019.06.024
PMID:31519488
Abstract

BACKGROUND

Slipped capital femoral epiphysis (SCFE) and Blount disease are strongly associated with pediatric obesity, yet they have only recently been identified as indications for consideration of metabolic and bariatric surgery (MBS).

OBJECTIVES

To describe the relationships between pediatric obesity, MBS, SCFE, and Blount disease.

SETTING

Nationwide database.

METHODS

The national inpatient sample was used to identify patients ≤20 years old with obesity who underwent MBS from 2007 to 2016. Presence of SCFE and Blount disease was similarly extracted.

RESULTS

The overall prevalence of SCFE and Blount disease among patients ≤20 years old is .02% for both (14,976, 11,238 patients, respectively) with no statistically significant change over the study period (P = .68, .07, respectively). The rates of SCFE and Blount disease in children with and without obesity are .46% versus .02% and .36% versus .01%, respectively (P < .001 for both). The mean age of patients with SCFE and obesity was 12 years old, while the mean age of those without obesity was 12.2 years old (P = .03). None of the children with obesity and SCFE underwent MBS. Similarly, the mean age of patients with Blount disease and obesity was 12.6 years old, while the mean age of those without obesity was 13.1 years old. Moreover, the mean age of children with Blount disease and obesity who underwent MBS was 16 years old (P < .001).

CONCLUSIONS

Orthopedic complications remain a persistent problem in the pediatric population who suffer from obesity. Despite being diagnosed at a young age, patients with SCFE and/or Blount disease are not undergoing MBS until their later adolescent years, potentially leading to unnecessary disease progression or recurrence of disease after orthopedic interventions. Therefore, SCFE and Blount disease should be considered indications for early consideration of MBS in this pediatric population.

摘要

背景

股骨颈骨骺滑脱(SCFE)和 Blount 病与小儿肥胖密切相关,但直到最近才被认为是代谢和减重手术(MBS)的适应证。

目的

描述小儿肥胖、MBS、SCFE 和 Blount 病之间的关系。

设置

全国性数据库。

方法

利用全国住院患者样本,确定 2007 年至 2016 年期间接受 MBS 的≤20 岁肥胖患者,并提取 SCFE 和 Blount 病的存在情况。

结果

≤20 岁患者中 SCFE 和 Blount 病的总体患病率均为 0.02%(分别为 14976 例和 11238 例),研究期间无统计学显著变化(P=0.68,P=0.07)。肥胖儿童与非肥胖儿童的 SCFE 和 Blount 病发生率分别为 0.46%比 0.02%和 0.36%比 0.01%(均 P<0.001)。患有 SCFE 和肥胖症的患者的平均年龄为 12 岁,而无肥胖症的患者的平均年龄为 12.2 岁(P=0.03)。没有肥胖和 SCFE 的儿童接受 MBS。同样,患有 Blount 病和肥胖症的患者的平均年龄为 12.6 岁,而无肥胖症的患者的平均年龄为 13.1 岁。此外,患有 Blount 病和肥胖症并接受 MBS 的儿童的平均年龄为 16 岁(P<0.001)。

结论

骨科并发症仍然是肥胖儿童人群中的一个持续存在的问题。尽管在年轻时就被诊断出患有 SCFE 和/或 Blount 病,但直到青少年后期才接受 MBS,这可能导致疾病不必要的进展或骨科干预后疾病复发。因此,SCFE 和 Blount 病应被视为此类儿科人群中早期考虑 MBS 的适应证。

相似文献

1
Slipped capital femoral epiphysis and Blount disease as indicators for early metabolic surgical intervention.股骨头骨骺滑脱和 Blount 病作为早期代谢性手术干预的指标。
Surg Obes Relat Dis. 2019 Oct;15(10):1836-1841. doi: 10.1016/j.soard.2019.06.024. Epub 2019 Jul 2.
2
Prevalence of Hypertension in Pediatric Tibia Vara and Slipped Capital Femoral Epiphysis.小儿胫骨内翻和股骨头骨骺滑脱症中高血压的患病率
J Pediatr Orthop. 2016 Dec;36(8):877-883. doi: 10.1097/BPO.0000000000000569.
3
Increased risk of Blount disease in obese children and adolescents with vitamin D deficiency.肥胖且缺乏维生素D的儿童和青少年患布朗特病的风险增加。
J Pediatr Orthop. 2010 Dec;30(8):879-82. doi: 10.1097/BPO.0b013e3181f5a0b3.
4
Childhood Obesity and Slipped Capital Femoral Epiphysis.儿童肥胖与股骨头骨骺滑脱。
Pediatrics. 2018 Nov;142(5). doi: 10.1542/peds.2018-1067. Epub 2018 Oct 22.
5
Decade-long Trends in Incidence of Slipped Capital Femoral Epiphysis in the United States: A Nationwide Database Analysis of Over 33 Million Patients.美国股骨颈滑脱症发病率的十年趋势:超过 3300 万患者的全国性数据库分析。
J Am Acad Orthop Surg Glob Res Rev. 2024 May 22;8(5). doi: 10.5435/JAAOSGlobal-D-24-00112. eCollection 2024 May 1.
6
Slipped capital femoral epiphysis: a population-based study.股骨头骨骺滑脱:一项基于人群的研究。
BMC Musculoskelet Disord. 2017 Jul 18;18(1):304. doi: 10.1186/s12891-017-1665-3.
7
Blount Disease and Obstructive Sleep Apnea: An Under-recognized Association?布隆特病与阻塞性睡眠呼吸暂停:一种被低估的关联?
J Pediatr Orthop. 2020 Nov/Dec;40(10):604-607. doi: 10.1097/BPO.0000000000001591.
8
Prepubertal onset of slipped capital femoral epiphysis associated with hypothyroidism: a case report and literature review.与甲状腺功能减退症相关的青春期前发病的股骨头骨骺滑脱:病例报告及文献复习。
BMC Endocr Disord. 2017 Sep 18;17(1):59. doi: 10.1186/s12902-017-0210-6.
9
Slipped capital femoral epiphysis: an epidemiological Nationwide study in Italy from 2001 to 2015.股骨头骨骺滑脱:2001 年至 2015 年意大利全国范围内的一项流行病学研究。
BMC Musculoskelet Disord. 2021 Jun 22;22(1):570. doi: 10.1186/s12891-021-04435-x.
10
Morphologic Features of the Contralateral Femur in Patients With Unilateral Slipped Capital Femoral Epiphysis Resembles Mild Slip Deformity: A Matched Cohort Study.单侧股骨头骨骺滑脱患者对侧股骨的形态特征类似于轻度滑脱畸形:一项配对队列研究。
Clin Orthop Relat Res. 2018 Apr;476(4):890-899. doi: 10.1007/s11999.0000000000000127.

引用本文的文献

1
A framework for studying race-based disparities in the use of metabolic and bariatric surgery for the management of pediatric obesity.一个用于研究在使用代谢和减重手术治疗小儿肥胖症方面基于种族差异的框架。
Am J Surg. 2021 Jul;222(1):49-51. doi: 10.1016/j.amjsurg.2020.11.043. Epub 2020 Dec 2.
2
Pharmacotherapy for the Treatment of Overweight and Obesity in Children, Adolescents, and Young Adults in a Large Health System in the US.美国大型医疗体系中儿童、青少年和青年超重与肥胖的药物治疗
Front Endocrinol (Lausanne). 2020 May 13;11:290. doi: 10.3389/fendo.2020.00290. eCollection 2020.
3
Preoperative considerations for the pediatric patient undergoing metabolic and bariatric surgery.
接受代谢和减重手术的儿科患者的术前注意事项。
Semin Pediatr Surg. 2020 Feb;29(1):150890. doi: 10.1016/j.sempedsurg.2020.150890. Epub 2020 Jan 20.