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单双黏膜微瓣 CO2 激光“滑动”技术在治疗医源性声门蹼中的应用:解剖和功能结果。

Single and double mucosal microflap CO laser "sliding" technique in the management of iatrogenic glottic web: anatomical and functional results.

机构信息

Unit of Otorhinolaryngology, Department of Surgery, Azienda Ospedaliero-Universitaria Di Cagliari, University of Cagliari, Cagliari, Italy.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia.

出版信息

Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3405-3412. doi: 10.1007/s00405-019-05632-0. Epub 2019 Sep 13.

DOI:10.1007/s00405-019-05632-0
PMID:31520161
Abstract

PURPOSE

An anterior glottic web consists of the formation of a bridge of scar tissue covered by epithelium between the anterior free edges of the true vocal cords and represents one of the most common complications of laryngeal endoscopic surgery for tumors involving the anterior commissure. Endoscopic surgery is the therapy of choice, but simple section of the web is burdened by a high recurrence rate. Topical application of mitomycin C, intracordal stents, and the use of mucosal microflaps have been proposed to improve outcomes. We report our experience with the use of single and double mucosal microflaps (sliding technique) during the management of iatrogenic anterior glottic web (IAGW).

METHODS

From November 2010 to December 2018, 30 patients (29 males, 1 female, mean age 65 years, range 47-87 years) were observed for IAGW, and 11 of these patients (36.7%) required surgical treatment. The Voice Handicap Index (VHI) and the GRBAS were used for the perceptive evaluation of pre- and post-operative voice quality.

RESULTS

A reduction of the web length was observed in all cases, and we did not observe any residual web at the mid-third of the glottis. The mean post-operative VHI score decreased from 45 to 24, and the mean post-operative GRBAS values were reduced from 2.8, 2.4, 2.3, 2.1, and 1.1 to 1.9, 1.4, 1.3, 1.1, and 0, respectively.

CONCLUSIONS

The microflap technique represents an effective and reproducible one-step procedure that, in expert hands, allows to obtain good anatomical and functional results in a high percentage of cases.

摘要

目的

前声门蹼由真声带前游离缘之间的桥状疤痕组织形成,表面覆盖上皮,是累及前连合的喉内镜肿瘤切除术的最常见并发症之一。内镜手术是首选的治疗方法,但单纯切开蹼会导致高复发率。已经提出了局部应用丝裂霉素 C、声带内支架和使用黏膜微瓣来改善结果。我们报告了在管理医源性前声门蹼(IAGW)时使用单个和双个黏膜微瓣(滑动技术)的经验。

方法

2010 年 11 月至 2018 年 12 月,观察了 30 例(29 名男性,1 名女性,平均年龄 65 岁,范围 47-87 岁)IAGW 患者,其中 11 例(36.7%)需要手术治疗。使用嗓音障碍指数(VHI)和 GRBAS 对术前和术后嗓音质量进行感知评估。

结果

所有病例均观察到蹼长度减少,且在声门中部未观察到任何残余蹼。术后 VHI 评分从 45 分降至 24 分,术后 GRBAS 值从 2.8、2.4、2.3、2.1 和 1.1 降至 1.9、1.4、1.3、1.1 和 0。

结论

微瓣技术是一种有效且可重复的一步法,在熟练的手中,该技术能使大多数病例获得良好的解剖和功能结果。

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2
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Ann Otol Rhinol Laryngol. 2018 Dec;127(12):946-952. doi: 10.1177/0003489418803651. Epub 2018 Sep 29.
3
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Cancers (Basel). 2023 Feb 27;15(5):1490. doi: 10.3390/cancers15051490.
年龄、声门下及前联合受累对接受CO2激光经口显微手术治疗的早期声门癌的预后价值:一项对261例患者的回顾性单中心队列研究
Eur Arch Otorhinolaryngol. 2018 May;275(5):1199-1210. doi: 10.1007/s00405-018-4890-y. Epub 2018 Feb 13.
4
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Eur Arch Otorhinolaryngol. 2017 Oct;274(10):3697-3702. doi: 10.1007/s00405-017-4689-2. Epub 2017 Aug 2.
5
Acquired Glottic Stenosis-The Ongoing Challenge: A Review of Etiology, Pathogenesis, and Surgical Management.获得性声门狭窄——持续的挑战:病因、发病机制及外科治疗综述
J Voice. 2015 Sep;29(5):646.e1-646.e10. doi: 10.1016/j.jvoice.2014.10.012. Epub 2015 Mar 17.
6
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7
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Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Feb;129(1):61-3. doi: 10.1016/j.anorl.2011.10.004. Epub 2012 Jan 13.