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一种采用内镜下纤维黏膜瓣重建前连合声门蹼的方法。

A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.

作者信息

Zeitels Steven M, Hillman Robert E

机构信息

1 Department of Surgery, Harvard Medical School, Boston, MA, USA.

2 Division of Laryngeal Surgery, Massachusetts General Hospital, Boston, MA, USA.

出版信息

Ann Otol Rhinol Laryngol. 2019 Mar;128(3_suppl):82S-93S. doi: 10.1177/0003489418820031.

Abstract

BACKGROUND

: Anterior-commissure (AC) cicatrization and web formation is a difficult problem that can result from a variety of clinical scenarios. An advancement-rotation flap utilizing papillomatous epithelium and subepithelial fibrous tissue has been previously described. For patients in whom there was not excessive redundant papillomatosis covering the AC web, including other clinical scenarios, a microlaryngoscopic procedure was designed to lengthen the glottal/subglottal aperture using substantial local fibro-mucosal tissue. Although it has been done for over a decade, this approach is not widely known and to our knowledge not photo-documented.

STUDY DESIGN

: Retrospective.

MATERIAL AND METHODS

: An analysis was done with Institutional Review Board approval that identified 42 patients who underwent 53 procedures to treat AC webs, which were reconstructed with local soft-tissue flaps and without any device/stent to maintain the glottal aperture. The microlaryngoscopic method and technical nuances for this approach with and without diseased epithelium are described and photo-documented. Tactical mucosal incisions were made to facilitate advancement and/or rotation of fibro-mucosal flaps with enough length to resurface the medial aspect of 1 vocal fold. The scarred submucosal soft tissue in the AC region was separated with cold instruments, and the flaps were sutured in position. Variations of this method are demonstrated mobilizing fibro-mucosal soft tissue from different locations, including the web itself, contralateral vocal fold, infrapetiole region, and/or the inner aspect of the thyroid lamina below the anterior-commissure tendon.

RESULTS

: Of the 53 cases in which anterior commissure glottal webs were reconstructed with endoscopic fibro-mucosal flaps, 31 of 53 had recurrent respiratory papillomatosis (RRP). Redundant RRP comprised the majority of the flap in 14 of 31 RRP cases. Fibro-mucosal tissue without a substantial amount of disease occurred in 17 of 31 RRP cases. Of the remaining 22 AC web cases, the primary diagnoses observed were: glottic cancer = 7 of 22, intraepithelial dysplasia = 10 of 22, glottic trauma = 3 of 22, congenital = 1 of 22, and radiotherapy = 1 of 22.

CONCLUSION

: Endolaryngeal utilization of local fibro-mucosal tissue to lengthen the glottal/subglottal aperture for AC webs is an effective strategy. It can be done without using devices or keels for webs that are congenital or from nonsurgical trauma, idiopathic disease, or postsurgical traumatic cicatrization of the anterior commissure subsequent to treatment of epithelial disease (eg, cancer, dysplasia, and RRP). Normalizing the architecture of the anterior commissure was a valuable asset in patients who require future treatment of epithelial diseases, especially in an office-based setting.

摘要

背景

前联合(AC)瘢痕形成和蹼状组织形成是一个棘手的问题,可由多种临床情况导致。此前已描述了一种利用乳头状上皮和上皮下纤维组织的推进旋转皮瓣。对于AC蹼没有过多覆盖其上的多余乳头状瘤病的患者,包括其他临床情况,设计了一种显微喉镜手术,利用大量局部纤维黏膜组织延长声门/声门下孔径。尽管该手术已开展了十多年,但这种方法并不广为人知,据我们所知也没有照片记录。

研究设计

回顾性研究。

材料与方法

在机构审查委员会批准下进行分析,确定42例患者接受了53次治疗AC蹼的手术,采用局部软组织皮瓣进行重建,且未使用任何装置/支架来维持声门孔径。描述并以照片记录了这种有或无病变上皮的方法的显微喉镜操作方法和技术细节。进行策略性黏膜切口,以促进纤维黏膜皮瓣的推进和/或旋转,皮瓣长度足以覆盖一侧声带的内侧表面。用冷器械分离AC区域瘢痕化的黏膜下软组织,然后将皮瓣缝合到位。展示了该方法的变体,即从不同位置动员纤维黏膜软组织,包括蹼本身、对侧声带、杓柄下区域和/或前联合腱下方甲状软骨板的内侧。

结果

在53例采用内镜下纤维黏膜皮瓣重建前联合声门蹼的病例中,53例中有31例患有复发性呼吸道乳头状瘤病(RRP)。在31例RRP病例中的14例中,多余的RRP构成了皮瓣的大部分。31例RRP病例中有17例出现没有大量病变的纤维黏膜组织。在其余22例AC蹼病例中,观察到的主要诊断为:声门癌 = 22例中的7例,上皮内发育异常 = 22例中的​10例,声门创伤 = 22例中的3例,先天性 = 22例中的1例,放疗后 = 22例中的1例。

结论

利用局部纤维黏膜组织在喉内延长AC蹼的声门/声门下孔径是一种有效的策略。对于先天性或非手术创伤、特发性疾病或上皮疾病(如癌症、发育异常和RRP)治疗后前联合的术后创伤性瘢痕形成导致的蹼,可以不使用装置或支架来完成。对于需要未来治疗上皮疾病的患者,尤其是在门诊环境中,使前联合结构正常化是一项有价值的优势。

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