University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, CA, USA.
University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, CA, USA.
Am J Surg. 2019 Dec;218(6):1189-1194. doi: 10.1016/j.amjsurg.2019.08.020. Epub 2019 Sep 10.
Marijuana has become legal in eight states since 2012. We hypothesized the incidence of marijuana-positive trauma patients and rate of mortality has increased post-legalization.
A single level-I trauma center was used to identify patients screening positive for marijuana on urine-toxicology. Patients in the pre-legalization and post-legalization periods were compared.
In the pre-legalization cohort 9.4% were marijuana-positive versus 11.0% in the post-legalization cohort (p = 0.001). Marijuana-positive patients post-legalization had higher rates of critical trauma activation (20.0% vs. 15.0%, p = 0.01) and mortality (2.6% vs. 1.2%, p = 0.03). In the pediatric (age 12-17) subgroup, the incidence of marijuana-positive patients did not change after legalization (pre: 39.3%, post: 46.4%, p = 0.24).
The incidence of marijuana-positive trauma patients increased post-legalization. Adult marijuana-positive trauma patients post-legalization were more likely to meet criteria for critical trauma activation and have a higher mortality rate. A subgroup of pediatric patients had an alarmingly high rate of marijuana use.
The rate of marijuana use among trauma patients increased post-legalization in California. The rate of critical trauma activation also increased as well as the mortality rate.
自 2012 年以来，大麻在八个州合法化。我们假设大麻阳性创伤患者的发病率和死亡率在合法化后有所增加。
使用单一一级创伤中心来识别尿液毒物筛查呈大麻阳性的患者。比较了合法化前后两个时期的患者。
在合法化前的队列中，有 9.4%的患者大麻呈阳性，而合法化后的队列中则有 11.0%（p=0.001）。合法化后大麻呈阳性的患者有更高的严重创伤激活率（20.0%比 15.0%，p=0.01）和死亡率（2.6%比 1.2%，p=0.03）。在儿科（12-17 岁）亚组中，合法化后大麻呈阳性的患者比例没有变化（前：39.3%，后：46.4%，p=0.24）。
大麻阳性创伤患者的发病率在合法化后有所增加。合法化后，成年大麻阳性创伤患者更有可能符合严重创伤激活的标准，且死亡率更高。一个儿科患者亚组的大麻使用率令人震惊地高。
在加利福尼亚州，大麻在创伤患者中的使用率在合法化后有所上升。严重创伤激活的发生率以及死亡率也有所增加。
