Wittenborn Julia, Clausen Annika, Zeppernick Felix, Stickeler Elmar, Meinhold-Heerlein Ivo
Klinik für Gynäkologie und Geburtsmedizin, Uniklinik RWTH Aachen, Aachen, Germany.
Zentrum für Frauenheilkunde und Geburtshilfe, Justus-Liebig-Universität Gießen, Gießen, Germany.
Geburtshilfe Frauenheilkd. 2019 Sep;79(9):969-975. doi: 10.1055/a-0903-2638. Epub 2019 Sep 11.
Hypothermia is defined as a decrease in body core temperature to below 36 °C. If intraoperative heat-preserving measures are omitted, a patient's temperature will fall by 1 - 2 °C. Even mild forms of intraoperative hypothermia can lead to a marked increase in morbidity and mortality. The temperature of the insufflation gas is usually disregarded in the treatment and prevention of hypothermia. This study was conducted to investigate the effect of body-temperature and humidified CO on the intraoperative temperature profile and avoidance of hypothermia in laparoscopic surgery. In this retrospective, non-randomised case control study, 110 patients whose planned operation lasted at least 60 minutes were identified from 376 patients by means of an algorithm. Dry (20% humidity) CO at room temperature was insufflated in 51 patients (control group). 59 patients were insufflated with humidified (98% humidity) CO at body temperature (37 °C) (study group). These conditions were achieved with the HumiGard MR860 Surgical Humidification System (Fisher & Paykel Healthcare Limited, Auckland, New Zealand). The intraoperative temperature profile was evaluated by measurements every 10 minutes. Statistical analysis was performed with IBM SPSS Statistics 23.0.0. The intraoperative temperature in the control group fell steadily, while a continuous rise in temperature was observed in the study group. Warming was demonstrated in the study group with a start-end temperature difference of 0.09 °C, which differed significantly from the control group, in which it was - 0.09 °C (p = 0.011). The middle-end difference of 0.11 °C showed even higher significance in favour of the warmed gas (p = 0.003). The rate of hypothermia at the start of the operation fell from 50 to 36% in the study group and increased from 36 to 42% in the control group. These results show that the use of body-temperature and humidified insufflation gas for laparoscopy can help to prevent intraoperative hypothermia.
体温过低被定义为人体核心温度降至36°C以下。如果术中省略保暖措施,患者体温将下降1-2°C。即使是轻度的术中体温过低也会导致发病率和死亡率显著增加。在体温过低的治疗和预防中,通常忽略了吹入气体的温度。本研究旨在探讨体温和加湿二氧化碳对腹腔镜手术术中体温曲线及预防体温过低的影响。在这项回顾性、非随机病例对照研究中,通过一种算法从376例患者中确定了110例计划手术持续至少60分钟的患者。51例患者(对照组)吹入室温下干燥(湿度20%)的二氧化碳。59例患者吹入体温(37°C)下加湿(湿度98%)的二氧化碳(研究组)。这些条件通过HumiGard MR860手术加湿系统(费雪派克医疗保健有限公司,新西兰奥克兰)实现。每10分钟测量一次以评估术中体温曲线。使用IBM SPSS Statistics 23.0.0进行统计分析。对照组术中体温稳步下降,而研究组观察到体温持续上升。研究组出现升温,起始-结束温差为0.09°C,与对照组显著不同,对照组为-0.09°C(p = 0.011)。中间-结束温差0.11°C对温热气体更具显著优势(p = 0.003)。研究组手术开始时体温过低的发生率从50%降至36%,而对照组从36%升至42%。这些结果表明,腹腔镜手术中使用体温和加湿的吹入气体有助于预防术中体温过低。