Takahara Kento, Mochizuki Yoichi, Ichimura Shinya, Kurebayashi Yutaka, Fujii Koji
Department of Neurosurgery, Shizuoka City Shimizu Hospital, Shizuoka.
Department of Pathology, Keio University School of Medicine, Tokyo, Japan.
Surg Neurol Int. 2019 Aug 2;10:152. doi: 10.25259/SNI_79_2019. eCollection 2019.
Urachal carcinoma (UC) is a rare variant of bladder carcinoma. Only seven cases of brain metastasis from UC have been reported in the literature thus far.
A 77-year-old female was diagnosed with a brain tumor in her left cerebellum 2 years after she underwent surgery for a primary UC in the bladder. Surgery was performed via a midline suboccipital approach and the tumor was totally removed. The excised lesion was pathologically diagnosed as a metastasis and displayed typical pathological features of urachal adenocarcinoma with abundant mucin mixed with signet ring cells. A recurrence was observed at the site of tumor removal 6 months after surgery, and then, gamma knife radiotherapy was performed to the lesion.
According to the five previously reported similar cases and our case, tumor removal is the treatment of choice. Routine whole brain radiotherapy is not the best treatment choice; however, local radiotherapy including conventional local radiotherapy or gamma knife radiotherapy could be implemented instead.
脐尿管癌（UC）是膀胱癌的一种罕见变体。迄今为止，文献中仅报道了7例脐尿管癌脑转移病例。
一名77岁女性在膀胱原发性脐尿管癌手术后2年被诊断出左小脑有脑肿瘤。通过枕下中线入路进行手术，肿瘤被完全切除。切除的病变经病理诊断为转移瘤，显示出脐尿管腺癌的典型病理特征，有大量黏液并混有印戒细胞。术后6个月在肿瘤切除部位观察到复发，随后对该病变进行了伽马刀放疗。
根据之前报道的5例类似病例及我们的病例，手术切除是首选治疗方法。常规全脑放疗并非最佳治疗选择；然而，可以采用局部放疗，包括传统局部放疗或伽马刀放疗。
