National Research Council, Institute of Neuroscience-Aging Branch, Padova, Italy.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
J Am Geriatr Soc. 2020 Jan;68(1):87-95. doi: 10.1111/jgs.16159. Epub 2019 Sep 17.
To determine whether there is an association between osteoarthritis (OA) and incident social isolation using data from the European Project on OSteoArthritis (EPOSA) study.
Prospective, observational study with 12 to 18 months of follow-up.
Community dwelling.
Older people living in six European countries.
Social isolation was assessed using the Lubben Social Network Scale and the Maastricht Social Participation Profile. Clinical OA of the hip, knee, and hand was assessed according to American College of Rheumatology criteria. Demographic characteristics, including age, sex, multijoint pain, and medical comorbidities, were assessed.
Of the 1967 individuals with complete baseline and follow-up data, 382 (19%) were socially isolated and 1585 were nonsocially isolated at baseline; of these individuals, 222 (13.9%) experienced social isolation during follow-up. Using logistic regression analyses, after adjustment for age, sex, and country, four factors were significantly associated with incident social isolation: clinical OA, cognitive impairment, depression, and worse walking time. Compared to those without OA at any site or with only hand OA, clinical OA of the hip and/or knee, combined or not with hand OA, led to a 1.47 times increased risk of social isolation (95% confidence interval = 1.03-2.09).
Clinical OA, present in one or two sites of the hip and knee, or in two or three sites of the hip, knee, and hand, increased the risk of social isolation, adjusting for cognitive impairment and depression and worse walking times. Clinicians should be aware that individuals with OA may be at greater risk of social isolation. J Am Geriatr Soc 68:87-95, 2019.
利用欧洲骨关节炎项目（EPOSA）研究的数据，确定骨关节炎（OA）与新发社会隔离之间是否存在关联。
前瞻性、观察性研究，随访时间为 12 至 18 个月。
社区居住。
居住在六个欧洲国家的老年人。
使用卢本社会网络量表和马斯特里赫特社会参与量表评估社会隔离。根据美国风湿病学会标准评估髋关节、膝关节和手部的临床 OA。评估了人口统计学特征，包括年龄、性别、多关节疼痛和合并症。
在 1967 名具有完整基线和随访数据的个体中，382 名（19%）处于社会隔离状态，1585 名在基线时未处于社会隔离状态；在这些个体中，222 名（13.9%）在随访期间经历了社会隔离。使用逻辑回归分析，在校正年龄、性别和国家后，有四个因素与新发社会隔离显著相关：临床 OA、认知障碍、抑郁和行走时间更差。与任何部位均无 OA 或仅手部 OA 的患者相比，髋关节和/或膝关节的临床 OA，无论是否合并手部 OA，均会使社会隔离的风险增加 1.47 倍（95%置信区间=1.03-2.09）。
髋关节和膝关节中一个或两个部位存在临床 OA，或髋关节、膝关节和手部中两个或三个部位存在临床 OA，调整认知障碍、抑郁和行走时间后，会增加社会隔离的风险。临床医生应意识到，OA 患者可能面临更大的社会隔离风险。美国老年学会杂志 68：87-95，2019 年。
