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一项针对老年人关节炎风险与认知能力下降的比较回顾性纵向研究。

A comparative retrospective longitudinal study of arthritis risk and cognitive decline in older adults.

机构信息

Mo-Im Kim Nursing Research Institute, Yonsei University College of Nursing, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, 03722, Republic of Korea.

出版信息

Sci Rep. 2024 Oct 21;14(1):24739. doi: 10.1038/s41598-024-75774-7.

Abstract

Arthritis often results in unmet healthcare needs for older adults with cognitive decline, who may struggle to communicate pain or recall symptoms. However, the risk factors for arthritis in this group remain underexplored. We addressed this gap by identifying and comparing arthritis risk factors among older adults with varying cognitive statuses. Data from 334 participants with cognitive decline and 808 participants with normal cognition were analysed using the Korean Longitudinal Study of Aging, tracking arthritis diagnoses over 12 years with Kaplan-Meier curves and Cox proportional hazards regression. Results showed 47.6% of older adults with cognitive decline developed arthritis, compared with 30.1% with normal cognition. Key risk factors for the cognitive decline group included depressive symptoms (hazard ratio [HR]: 1.87), living alone (HR: 1.66), infrequent social interactions (HR: 1.42), and greater dependency in daily activities (HR: 1.41). In the normal cognition group, additional chronic illnesses (HR: 1.41) and higher body mass index (HR: 1.09) were significant risk factors. Understanding these distinct risk factors is crucial for preventing and managing arthritis among at risk groups. Moreover, these findings can assist in developing comprehensive public health strategies integrating mental health and social support to improve health outcomes for older adults with cognitive decline.

摘要

关节炎常导致认知能力下降的老年人无法满足医疗保健需求,因为他们可能难以表达疼痛或回忆症状。然而,这一群体的关节炎风险因素仍未得到充分探索。我们通过确定和比较认知状态不同的老年人的关节炎风险因素来解决这一差距。使用韩国老龄化纵向研究的数据,对 334 名认知能力下降的参与者和 808 名认知能力正常的参与者进行了分析,使用 Kaplan-Meier 曲线和 Cox 比例风险回归追踪了 12 年的关节炎诊断。结果显示,认知能力下降的老年人中有 47.6%发展为关节炎,而认知能力正常的老年人中有 30.1%发展为关节炎。认知能力下降组的主要风险因素包括抑郁症状(风险比 [HR]:1.87)、独居(HR:1.66)、社交互动不频繁(HR:1.42)和日常生活活动依赖性更大(HR:1.41)。在认知能力正常的组中,其他慢性疾病(HR:1.41)和更高的体重指数(HR:1.09)也是显著的风险因素。了解这些不同的风险因素对于预防和管理高危人群的关节炎至关重要。此外,这些发现可以帮助制定综合公共卫生策略,整合心理健康和社会支持,以改善认知能力下降的老年人的健康结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ede9/11494171/c6703a443250/41598_2024_75774_Fig1_HTML.jpg

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