Institute of Medical Physics and Radiation Protection (IMPS), THM University of Applied Sciences Giessen, 35390 Giessen, Germany. GSI Helmholtzzentrum für Schwerionenforschung, 64291 Darmstadt, Germany.
Phys Med Biol. 2019 Oct 16;64(20):205012. doi: 10.1088/1361-6560/ab4511.
Measured cross sections for the production of the PET isotopes [Formula: see text], [Formula: see text] and [Formula: see text] from carbon and oxygen targets induced by protons (40-220 [Formula: see text]) and carbon ions (65-430 [Formula: see text]) are presented. These data were obtained via activation measurements of irradiated graphite and beryllium oxide targets using a set of three scintillators coupled by a coincidence logic. The measured cross sections are relevant for the PET particle range verification method where accurate predictions of the [Formula: see text] emitter distribution produced by therapeutic beams in the patient tissue are required. The presented dataset is useful for validation and optimization of the nuclear reaction models within Monte Carlo transport codes. For protons the agreement of a radiation transport calculation using the measured cross sections with a thick target PET measurement is demonstrated.
本文给出了质子（40-220 MeV）和碳离子（65-430 MeV）辐照石墨和氧化铍靶时，通过三个闪烁体的符合逻辑测量[公式：见正文]、[公式：见正文]和[公式：见正文]放射性核素的产生截面。这些数据对于正电子发射断层扫描（PET）粒子射程验证方法是有用的，该方法需要准确预测治疗束在患者组织中产生的[公式：见正文]放射性核素分布。所提出的数据集可用于验证和优化蒙特卡罗输运代码中的核反应模型。对于质子，本文证明了使用测量截面的辐射输运计算与厚靶 PET 测量的一致性。
