流感病毒血凝素在膜融合中的作用。
The role of influenza virus haemagglutinin in membrane fusion.
作者信息
Wharton S A
机构信息
Division of Virology, National Institute for Medical Research, Mill Hill, London, UK.
出版信息
Microbiol Sci. 1987 Apr;4(4):119-24.
PMID:3153182
Abstract
An acid-induced conformational change in influenza virus haemagglutinin triggers the virus to fuse with the endosomal membrane of a host cell during infection. Structural aspects of this change are discussed along with the possible haemagglutinin-mediated processes which occur during membrane fusion.
摘要
酸性诱导的流感病毒血凝素构象变化会促使病毒在感染期间与宿主细胞的内体膜融合。本文将讨论这一变化的结构方面，以及膜融合过程中可能发生的血凝素介导的过程。
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