Baker D, Agard D A
Department of Biochemistry, University of Washington, Seattle 98195.
Structure. 1994 Oct 15;2(10):907-10. doi: 10.1016/s0969-2126(94)00091-3.
In response to decreased pH, influenza hemagglutinin changes to a more stable conformation. Such changes, which can be controlled thermodynamically or kinetically, are the method by which many biological 'switches' are thrown.
为应对pH值降低,流感血凝素会转变为更稳定的构象。这种可通过热力学或动力学控制的变化,是许多生物“开关”发挥作用的方式。