β-内酰胺酶：老问题的新变化
Beta-lactamases: a new twist to an old problem.
作者信息
Nichols W W
机构信息
Public Health Laboratory, John Radcliffe Hospital, Headington, Oxford, UK.
出版信息
Microbiol Sci. 1987 May;4(5):147-8.
PMID:3153189
Abstract
Beta-lactamases have been known for as long as penicillin has been used for chemotherapy. Their importance to man is that they are overwhelmingly responsible for bacterial resistance to beta-lactam antibiotics, i.e. those similar to penicillin and the cephalosporins.
摘要
自青霉素被用于化疗以来，人们就已经知道了β-内酰胺酶。它们对人类的重要性在于，细菌对β-内酰胺抗生素（即那些与青霉素和头孢菌素类似的抗生素）产生耐药性，绝大多数原因都在于β-内酰胺酶。
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