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Eculizumab as a bridge to immunosuppressive therapy in severe cold agglutinin disease of anti-Pr specificity.依库珠单抗作为抗-Pr特异性严重冷凝集素病免疫抑制治疗的桥梁。
Clin Case Rep. 2015 Nov;3(11):942-4. doi: 10.1002/ccr3.399. Epub 2015 Sep 29.
2
Transfusion medicine illustrated. The role of plasmapheresis in the multimodal treatment of anti-Pr cold agglutinin disease.
Transfusion. 2010 Oct;50(10):2100-1. doi: 10.1111/j.1537-2995.2010.02809.x.
3
Restriction in the repertoire of the immunoglobulin light chain subgroup in pathological cold agglutinins with anti-Pr specificity.具有抗-Pr特异性的病理性冷凝集素中免疫球蛋白轻链亚群库的限制。
Vox Sang. 2004 Feb;86(2):141-7. doi: 10.1111/j.0042-9007.2004.00401.x.
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Haemolytic-anaemia relapses after immunisation and pertussis.
Lancet. 1967 Oct 21;2(7521):894-5. doi: 10.1016/s0140-6736(67)92633-5.
5
Transfusion support with RBCs from an Mk homozygote in a case of autoimmune hemolytic anemia following diphtheria-pertussis-tetanus vaccination.在白喉-百日咳-破伤风疫苗接种后发生自身免疫性溶血性贫血的病例中，使用来自Mk纯合子的红细胞进行输血支持。
Transfusion. 2002 May;42(5):567-71. doi: 10.1046/j.1537-2995.2002.00093.x.
6
Autoimmune hemolytic anemia caused by IgG lambda-monotypic cold agglutinins of anti-Pr specificity after rubella infection.风疹感染后由抗-Pr特异性的IgG λ单型冷凝集素引起的自身免疫性溶血性贫血。
Transfusion. 2001 Apr;41(4):488-92. doi: 10.1046/j.1537-2995.2001.41040488.x.
7
Vaccination-associated immune hemolytic anemia in two children.两名儿童的疫苗接种相关免疫性溶血性贫血
Transfusion. 2000 Aug;40(8):907-9. doi: 10.1046/j.1537-2995.2000.40080907.x.
8
Association of bacterial carbohydrate-specific cold agglutinin antibody production with immunization by group C, group B type III, and Streptococcus pneumoniae type XIV streptococcal vaccines.C 群、B 群Ⅲ型及肺炎链球菌 14 型链球菌疫苗免疫接种与细菌碳水化合物特异性冷凝集素抗体产生的关联。
Infect Immun. 1983 Jul;41(1):205-13. doi: 10.1128/iai.41.1.205-213.1983.
9
[Autoimmune hemolysis caused by anti-Pr].
Infusionsther Klin Ernahr. 1985 Aug;12(4):181-4.
10
Etiologic aspects of cold agglutinin disease: evidence for cytogenetically defined clones of lymphoid cells and the demonstration that an anti-Pr cold autoantibody is derived from a chromosomally aberrant B cell clone.冷凝集素病的病因学方面：淋巴细胞细胞遗传学定义克隆的证据以及抗-Pr 冷自身抗体源自染色体异常 B 细胞克隆的证明。
Blood. 1986 Jun;67(6):1705-9.

肺炎球菌疫苗接种后抗-Pr抗体诱发的冷凝集素型自身免疫性溶血性贫血。

Anti-Pr antibody induced cold autoimmune hemolytic anemia following pneumococcal vaccination.

作者信息

Bowen Laurel, LePage Nichole, Lewandowska Magdalena, Waxman Dan A

机构信息

Department of Pathology and Laboratory Medicine Indiana University School of Medicine Indianapolis IN USA.

Department of Hematology Oncology Indiana University Health Indianapolis IN USA.

出版信息

Clin Case Rep. 2019 Aug 9;7(9):1763-1765. doi: 10.1002/ccr3.2365. eCollection 2019 Sep.

DOI:10.1002/ccr3.2365
PMID:31534744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6745373/
Abstract

While rare, vaccination-induced autoantibodies can occur outside of the pediatric population. This diagnosis should be considered after infectious and lymphoproliferative disorders are ruled out. Clinical management will depend on the individual case, but all patients should be monitored closely.

摘要

虽然罕见，但疫苗接种诱导的自身抗体可在儿科人群以外出现。在排除感染性和淋巴增殖性疾病后应考虑这一诊断。临床管理将取决于具体病例，但所有患者都应密切监测。