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药物诱导睡眠内镜检查在小儿阻塞性睡眠呼吸暂停低通气综合征治疗中的作用。

Contribution of drug-induced sleep endoscopy to the management of pediatric obstructive sleep apnea/hypopnea syndrome.

机构信息

Service d'ORL et Chirurgie Cervico Faciale, UAM d'ORL Pédiatrique, Hôpital Gui de-Chauliac, CHU de Montpellier, Université de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

Service d'ORL et Chirurgie Cervico Faciale, UAM d'ORL Pédiatrique, Hôpital Gui de-Chauliac, CHU de Montpellier, Université de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Nov;136(6):447-454. doi: 10.1016/j.anorl.2019.09.001. Epub 2019 Sep 16.

Abstract

OBJECTIVES

The role of drug-induced sleep endoscopy (DISE) in the management of obstructive sleep apnea/hypopnea syndrome (OSAHS) is not precisely defined in children. The primary objective of this study was to describe DISE-induced revision of airway obstruction site location and the ensuing treatment changes in children with OSAHS. Secondary objectives were to analyze the correlation of number of obstruction sites found on DISE with apnea-hypopnea index (AHI) and with type of OSAHS.

MATERIAL AND METHODS

A retrospective single-center study included 31 children (mean age: 5.5±2.6years) undergoing DISE for management of OSAHS between 2015 and 2018. Revisions of airway obstruction site location and in treatment were noted. The correlation of number of obstruction sites with AHI and with type of OSAHS was analyzed.

RESULTS

Airway obstruction site location was reconsidered in 77% of children (n=24), modifying treatment in 45.2% (n=14). There was no significant correlation between number of obstruction sites and AHI: Spearman coefficient 0.20 (P=0.26). Patients with type-III OSAHS did not show more obstruction sites than others: respectively, 2.0 versus 1.8 (P=0.40).

CONCLUSION

DISE induced significant revision of the location and change in treatment of obstruction sites in children with OSAHS. Systematic implementation, especially in type-I OSAHS, would allow more precise pre-therapeutic classification and treatment adapted to actual airway obstruction.

摘要

目的

药物诱导睡眠内镜(DISE)在儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)中的作用尚未明确界定。本研究的主要目的是描述 DISE 诱导的气道阻塞部位位置的改变,以及随后对 OSAHS 患儿的治疗变化。次要目的是分析 DISE 发现的阻塞部位数量与呼吸暂停低通气指数(AHI)和 OSAHS 类型之间的相关性。

材料和方法

这是一项回顾性单中心研究,纳入了 2015 年至 2018 年间因 OSAHS 接受 DISE 治疗的 31 名儿童(平均年龄:5.5±2.6 岁)。记录气道阻塞部位位置和治疗的变化。分析阻塞部位数量与 AHI 和 OSAHS 类型的相关性。

结果

77%(n=24)的患儿重新考虑了气道阻塞部位的位置,45.2%(n=14)的患儿改变了治疗方案。阻塞部位数量与 AHI 之间无显著相关性:Spearman 系数 0.20(P=0.26)。III 型 OSAHS 患儿的阻塞部位并不比其他类型的患儿多:分别为 2.0 与 1.8(P=0.40)。

结论

DISE 诱导 OSAHS 患儿气道阻塞部位的位置和治疗发生了显著改变。系统实施 DISE,特别是在 I 型 OSAHS 中,可以更准确地进行治疗前分类,并根据实际气道阻塞情况进行治疗。

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