Wake Forest University and Baptist Health, Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
University of Illinois College of Medicine at Chicago, Chicago, IL, USA.
Abdom Radiol (NY). 2021 Jan;46(1):257-267. doi: 10.1007/s00261-020-02630-3. Epub 2020 Jul 6.
Carcinoma of Unknown Primary presenting primarily as hepatic metastases encompasses a dismal subgroup of tumors with a median survival of 5.9 months. Adenocarcinoma is the most common histological subtype identified upon biopsy and the primary tumor remains undetectable in the majority of cases despite extensive workup. It is important to have a validated and standardized algorithm to follow these tumors to avoid unnecessary tests, as the wishes and health status of the patient represent the principal concerns. The purpose of this paper is to briefly review the current literature on carcinoma of unknown primary with hepatic metastases and propose a standardized diagnostic approach.
原发性不明癌症主要表现为肝转移，包括一组预后极差的肿瘤亚群，中位生存期为 5.9 个月。腺癌是活检中最常见的组织学亚型，尽管进行了广泛的检查，但大多数情况下仍无法检测到原发性肿瘤。拥有经过验证和标准化的算法来监测这些肿瘤非常重要，可以避免不必要的检查，因为患者的意愿和健康状况是主要关注点。本文的目的是简要回顾原发性不明癌症伴肝转移的现有文献，并提出一种标准化的诊断方法。
