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1
Elevated adjuvanticity of non-acid-fast mycobacteria.非抗酸分枝杆菌佐剂活性增强。
Infect Immun. 1979 Oct;26(1):19-24. doi: 10.1128/iai.26.1.19-24.1979.
2
Live but not heat-killed mycobacteria cause rapid chemotaxis of large numbers of eosinophils in vivo and are ingested by the attracted granulocytes.活的而非热灭活的分枝杆菌可在体内引起大量嗜酸性粒细胞的快速趋化作用，并被吸引来的粒细胞吞噬。
Infect Immun. 1991 Sep;59(9):3009-14. doi: 10.1128/iai.59.9.3009-3014.1991.
3
The efficacy of live tuberculosis vaccines after presensitization with Mycobacterium avium.用鸟分枝杆菌进行预致敏后活结核疫苗的疗效。
Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):73-9. doi: 10.1016/j.tube.2004.09.007. Epub 2004 Dec 28.
4
[Adjuvant activity of peptidoglyoans from mycobacteria].[分枝杆菌肽聚糖的佐剂活性]
C R Acad Hebd Seances Acad Sci D. 1974 Feb 4;278(6):799-801.
5
Trehalose dimycolate elicits eosinophilic skin hypersensitivity in mycobacteria-infected guinea pigs.海藻糖二分枝菌酸酯可引发感染分枝杆菌的豚鼠出现嗜酸性皮肤超敏反应。
J Immunol. 2008 Dec 15;181(12):8528-33. doi: 10.4049/jimmunol.181.12.8528.
6
[The formation of delayed hypersensitivity to mycobacterial antigens].[对分枝杆菌抗原迟发型超敏反应的形成]
Zh Mikrobiol Epidemiol Immunobiol. 1991 Apr(4):66-8.
7
[Antigenic and allergenic properties of various atypical Mycobacteria and Mycobacterium avium. II. Skin reactions to homologous and heterologous PPD preparations in artificially sensitized guinea pigs].[各种非典型分枝杆菌和鸟分枝杆菌的抗原性和变应原性。II. 人工致敏豚鼠对同源和异源结核菌素纯蛋白衍生物制剂的皮肤反应]
Pol Arch Weter. 1979;22(1):19-27.
8
Differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions.通过“体内”和“体外”迟发型超敏反应鉴别分枝杆菌。
Rev Bras Pesqui Med Biol. 1978 Jun;11(2-3):111-5.
9
Molecular and immunological analyses of the Mycobacterium avium homolog of the immunodominant Mycobacterium leprae 35-kilodalton protein.麻风分枝杆菌免疫显性35千道尔顿蛋白的鸟分枝杆菌同源物的分子和免疫学分析。
Infect Immun. 1998 Jun;66(6):2684-90. doi: 10.1128/IAI.66.6.2684-2690.1998.
10
[A comparative study of delayed hypersensitivity due to mycobacteria and their isolated protein fractions].[分枝杆菌及其分离蛋白组分所致迟发型超敏反应的比较研究]
Zh Mikrobiol Epidemiol Immunobiol. 1989 Jul(7):84-9.

本文引用的文献

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Studies on antibody production. IV. The role of a wax fraction of Mycobacterium tuberculosis in adjuvant emulsions on the production of antibody to egg albumin.抗体产生的研究。IV. 结核分枝杆菌蜡质部分在佐剂乳剂中对卵清蛋白抗体产生的作用。
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2
FRACTIONATION AND CHARACTERIZATION OF WAX D, A MACROMOLECULAR PEPTIDOGLYCOLIPID OF MYCOBACTERIUM TUBERCULOSIS. I. BIOCHEMICAL INVESTIGATIONS OF WAX D OF HUMAN STRAIN H37RA.结核分枝杆菌大分子肽糖脂蜡质D的分级分离与特性研究。I. 人源菌株H37RA蜡质D的生化研究
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3
LYSIS OF ISOLATED BCG CELL WALLS WITH ENZYMES. 2. DEMONSTRATION OF 'BOUND WAX D' AS A COMPONENT OF BCG CELL WALLS.用酶裂解卡介苗（BCG）分离细胞壁。2. 证明“结合蜡D”是卡介苗细胞壁的一个组成成分。
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4
Sites of antibody production in the guinea-pig; the relation between in vitro synthesis of anti-ovalbumin and gamma-globulin and distribution of antibody-containing plasma cells.豚鼠体内抗体产生的部位；抗卵清蛋白和γ球蛋白的体外合成与含抗体浆细胞分布之间的关系
Br J Exp Pathol. 1956 Feb;37(1):61-74.
5
Quantitative study of the granulopectic activity of the reticulo-endothelial system. II. A study of the kinetics of the R. E. S. in relation to the dose of carbon injected; relationship between the weight of the organs and their activity.网状内皮系统粒细胞吞噬活性的定量研究。II. 网状内皮系统动力学与注入碳剂量的关系；器官重量与其活性之间的关系。
Br J Exp Pathol. 1953 Aug;34(4):441-57.
6
The role of tubercle bacilli in adjuvant emulsions on antibody production to egg albumin.结核杆菌在佐剂乳剂中对卵白蛋白抗体产生的作用。
J Immunol. 1952 Dec;69(6):611-8.
7
The influence of age of culture on the production of adjuvant-active peptidoglycolipids by saprophytic mycobacteria.培养物年龄对腐生分枝杆菌产生佐剂活性肽糖脂的影响。
Immunology. 1967 Mar;12(3):349-59.
8
Glutaraldehyde, cyanuric chloride and tetrazotized O-dianisidine as coupling reagents in the passive hemagglutination test.戊二醛、三聚氯氰和四氮唑化邻联茴香胺作为被动血凝试验中的偶联试剂。
Immunochemistry. 1969 Jan;6(1):67-76. doi: 10.1016/0019-2791(69)90179-7.
9
[The chemical structure of wax D, a macromolecular peptidoglycolipid of human strains of Mycobacterium tuberculosis].[蜡质D的化学结构，一种人结核分枝杆菌菌株的大分子肽糖脂]
Eur J Biochem. 1971 Jan;18(2):287-91. doi: 10.1111/j.1432-1033.1971.tb01242.x.
10
Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. I. Stimulation by phytohaemagglutinin.有丝分裂原刺激的人外周血淋巴细胞碳水化合物代谢的变化。I. 植物血凝素刺激
Biochim Biophys Acta. 1970 Dec 29;222(3):565-82. doi: 10.1016/0304-4165(70)90182-0.

非抗酸分枝杆菌佐剂活性增强。

Elevated adjuvanticity of non-acid-fast mycobacteria.

作者信息

Kondo Y, Toida T

出版信息

Infect Immun. 1979 Oct;26(1):19-24. doi: 10.1128/iai.26.1.19-24.1979.

DOI:10.1128/iai.26.1.19-24.1979
PMID:315375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414568/
Abstract

Administration to guinea pigs of non-acid-fast (NAF) Mycobacterium avium resulted in a sevenfold greater circulating antibody response than that for the animals receiving ovalbumin in Freund incomplete adjuvant alone. The ability of NAF M. avium on induction of delayed hypersensitivity was comparable or somewhat stronger than that of normal M. avium. The in vivo enhancement of circulating antibody response by NAF M. avium associated with a marked stimulating effect of it on proliferation of B cells in regional sites. Induction of local granuloma at the injection site of NAF M. avium was less than that induced by injection of normal M. avium. Phagocytic activity of the reticuloendothelial system in mice was also greatly increased by administration of NAF M. avium.

摘要

给豚鼠接种非抗酸（NAF）鸟分枝杆菌后，其循环抗体反应比仅接受弗氏不完全佐剂中卵清蛋白的动物高7倍。NAF鸟分枝杆菌诱导迟发型超敏反应的能力与正常鸟分枝杆菌相当或稍强。NAF鸟分枝杆菌对循环抗体反应的体内增强作用与其对局部区域B细胞增殖的显著刺激作用有关。NAF鸟分枝杆菌注射部位的局部肉芽肿形成比正常鸟分枝杆菌注射诱导的要少。给小鼠施用NAF鸟分枝杆菌也可大大提高网状内皮系统的吞噬活性。