Hashmi Hamza, Alexander Jonathan Struan
Division of Medical Oncology and Hematology, University of Louisville, Louisville, Kentucky, USA.
Department of Internal Medicine, University of Louisville, Louisville, KY, USA.
BMJ Case Rep. 2019 Sep 18;12(9):e231096. doi: 10.1136/bcr-2019-231096.
AIDS-related Kaposi sarcoma (KS) is a malignancy seen in patients with HIV/AIDS that results from unrestrained human herpesvirus 8 infection. It can have an atypical presentation and an aggressive clinical course in patients with uncontrolled HIV infection. We present an interesting case of AIDS-related KS with an atypical initial presentation with skin nodules and debilitating lymphoedema. Patient was successfully managed with supportive measures, antiretroviral therapy and systemic chemotherapy.
艾滋病相关的卡波西肉瘤(KS)是一种在人类免疫缺陷病毒/艾滋病(HIV/AIDS)患者中出现的恶性肿瘤,由人类疱疹病毒8型不受控制的感染引起。在HIV感染未得到控制的患者中,它可能有非典型表现和侵袭性临床病程。我们报告一例有趣的艾滋病相关KS病例,其最初表现为非典型的皮肤结节和使人衰弱的淋巴水肿。患者通过支持措施、抗逆转录病毒疗法和全身化疗成功得到治疗。