Chatterjee K, Opie L H
University of California, San Francisco 94143.
Cardiovasc Drugs Ther. 1987;1(1):1-8. doi: 10.1007/BF02125827.
ACE inhibitors have emerged as important pharmacologic agents for treatment of hypertension and heart failure. Attenuation or inhibition of angiotensin mediated vasoconstriction appears to be the principal mechanism for the reduction of arterial pressure and systemic vascular resistance.
血管紧张素转换酶抑制剂已成为治疗高血压和心力衰竭的重要药物。血管紧张素介导的血管收缩作用减弱或受到抑制似乎是动脉压和全身血管阻力降低的主要机制。